Reactome | TGOLN2 [cytoplasmic vesicle membrane]

TGOLN2 [cytoplasmic vesicle membrane]

Stable Identifier

R-HSA-429818

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytoplasmic vesicle membrane

Synonyms

Trans-Golgi network integral membrane protein 2, TGON2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43493 TGOLN2

Gene Names

TGOLN2, TGN46, TGN51

Chain

signal peptide:1-21, chain:22-437

Reference Genes

BioGPS Gene:10618 TGOLN2

COSMIC (genes):TGOLN2 TGOLN2

CTD Gene:10618 TGOLN2

dbSNP Gene:10618 TGOLN2

ENSEMBL:ENSG00000152291 TGOLN2

HGNC:15450 TGOLN2

KEGG Gene (Homo sapiens):10618 TGOLN2

Monarch:10618 TGOLN2

NCBI Gene:10618 TGOLN2

OMIM:603062 TGOLN2

UCSC:O43493 TGOLN2

Reference Transcript

Other Identifiers

0002260162

10618

11489

11716901_s_at

11716902_a_at

11716903_a_at

11716904_s_at

11755687_x_at

12609

12723

1566473_3p_a_at

1566473_a_at

16899619

203833_s_at

203834_s_at

212040_3p_at

212040_at

212043_at

2491521

2562200

2562201

2562202

2562203

2562204

2562205

2562209

2562210

2562211

2562212

2562213

2562214

2562215

2562216

2562217

2562218

2562220

2562221

2562222

2562224

2562226

2562228

2562230

31827_s_at

31828_r_at

31829_r_at

38993_r_at

8053388

A_23_P209933

A_24_P413988

AAB96906

AAB96907

AAB96908

AAC39539

AAC39541

AAC39542

AAH08461

AAH28219

AAY24095

AC093162

AF027515

AF027516

AF029313

AF029314

AF029315

AF029316

AK126465

AK222829

AK223063

AK312479

BAC86559

BAD96549

BAD96783

BAG35383

BC008461

BC028219

BX640868

CAA64002

CAB011489

CAE45926

CCDS46351

CCDS56126

CCDS56127

CH471053

EAW99535

EAW99536

EAW99539

ENSG00000152291

ENSP00000282120

ENSP00000366603

ENSP00000381312

ENSP00000386443

ENSP00000391190

ENST00000282120

ENST00000282120.6

ENST00000377386

ENST00000377386.7

ENST00000398263

ENST00000398263.6

ENST00000409232

ENST00000409232.7

ENST00000444342

ENST00000444342.2

EntrezGene:10618

EntrezGene:TGOLN2

g5454115_3p_a_at

GE81643

GE86506

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005737

GO:0005768

GO:0005783

GO:0005788

GO:0005794

GO:0005802

GO:0005886

GO:0006464

GO:0008150

GO:0016020

GO:0016021

GO:0030133

GO:0030140

GO:0030665

GO:0031410

GO:0043226

GO:0043687

GO:0044267

GO:0061024

HGNC:15450

HPA012609

HPA012723

Hs.110771.0.S1_3p_x_at

Hs.110771.0.S2_3p_at

Hs.14894.0.S1_3p_a_at

Hs.14894.0.S1_3p_s_at

ILMN_1651735

MIM:603062

NM_001206840

NM_001206841

NM_001206844

NM_001368096

NM_006464

NP_001193769

NP_001193770

NP_001193773

NP_001355025

NP_006455

PF17818

PH_hs_0001402

PH_hs_0040170

TC02002035.hg

TGOLN2

TGOLN2-201

TGOLN2-202

TGOLN2-203

TGOLN2-205

TGOLN2-206

U62390

UPI0000072C61

UPI0000208801

UPI000020880A

UPI0000EE2512

UPI0004E4CA4A

X94333

X94333_at

Participant Of

hasCandidate

Golgi-associated Vesicle Cargo [cytoplasmic vesicle membrane]

Other forms of this molecule

TGOLN2 [clathrin-coated endocytic vesicle membrane]

TGOLN2 [plasma membrane]

TGOLN2 [Golgi membrane]

TGOLN2 [trans-Golgi network membrane]

TGOLN2 [transport vesicle]

p-TGOLN2 [endoplasmic reticulum lumen]

TGOLN2 [endoplasmic reticulum lumen]

Inferred To

TGOLN2 [cytoplasmic vesicle membrane] (Bos taurus)

TGOLN2 [cytoplasmic vesicle membrane] (Canis familiaris)

TGOLN2 [cytoplasmic vesicle membrane] (Danio rerio)

TGOLN2 [cytoplasmic vesicle membrane] (Mus musculus)

TGOLN2 [cytoplasmic vesicle membrane] (Rattus norvegicus)

TGOLN2 [cytoplasmic vesicle membrane] (Sus scrofa)

Cross References

RefSeq

NP_001193769.1, NP_001193770.1, NP_001193773.1, NP_006455.2

OpenTargets

ENSG00000152291

GeneCards

O43493

PRO

O43493

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H3P7 ACBD3	1	ACBD3 [Golgi membrane] (R-HSA-8874981)	0.577	5
UniProt:P27986 PIK3R1	15	PIK3R1 K379E [plasma membrane] (R-HSA-8944148) PIK3R1 G376R [plasma membrane] (R-HSA-2399717) PIK3R1 Y463_L466del [plasma membrane] (R-HSA-2399546) PIK3R1 H450_E451del [plasma membrane] (R-HSA-2399545) PIK3R1 R574_T576del [plasma membrane] (R-HSA-2399544) PIK3R1 D560Y [plasma membrane] (R-HSA-2399421) PIK3R1 N564D [plasma membrane] (R-HSA-2399427) PIK3R1 K459del [plasma membrane] (R-HSA-2399554) PIK3R1 N564K [plasma membrane] (R-HSA-2399431) PIK3R1 D560H [plasma membrane] (R-HSA-2399432) PIK3R1 R574I [plasma membrane] (R-HSA-2399536) PIK3R1 R574T [plasma membrane] (R-HSA-2399540) K63polyUb-PIK3R1 [cytosol] (R-HSA-3080572) PIK3R1 [plasma membrane] (R-HSA-198365) PIK3R1 [cytosol] (R-HSA-74789)	0.564	2
UniProt:Q9NZ52 GGA3	3	GGA3 [recycling endosome membrane] (R-HSA-8875655) GGA3 [endosome membrane] (R-HSA-5692936) GGA3 [early endosome membrane] (R-HSA-8854137)	0.491	3
UniProt:Q07065 CKAP4	7	PALM-C100-CKAP4 [plasma membrane] (R-HSA-5686280) PALM-C100-CKAP4 [lamellar body] (R-HSA-5686285) CKAP4 [azurophil granule membrane] (R-HSA-6799559) CKAP4 [plasma membrane] (R-HSA-5686306) CKAP4 [specific granule membrane] (R-HSA-6799552) p-CKAP4 [endoplasmic reticulum lumen] (R-HSA-8956926) CKAP4 [endoplasmic reticulum lumen] (R-HSA-8956737)	0.462	2
UniProt:Q04721 NOTCH2	18	NOTCH2(1582-1665) [extracellular region] (R-HSA-157652) NICD2 [nucleoplasm] (R-HSA-157942) NOTCH2(1666-1696) [plasma membrane] (R-HSA-157628) NEXT2 [plasma membrane] (R-HSA-157225) NICD2 [cytosol] (R-HSA-157642) Glc,GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911428) Glc,Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911417) Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911505) FRINGE-modified NOTCH2 Extracellular Fragment (NECD2) [plasma membrane] (R-HSA-1911518) FRINGE-modified NOTCH2 extracellular fragment (NECD2) [Golgi membrane] (R-HSA-1911520) Pre-NOTCH2 [endoplasmic reticulum membrane] (R-HSA-157025) 18xFucT-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane] (R-HSA-1467363) 18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane] (R-HSA-1467379) 18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [Golgi membrane] (R-HSA-1472874) NOTCH2(1582-2471) [plasma membrane] (R-HSA-157228) 18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [extracellular region] (R-HSA-1983678) NOTCH2(1582-2471) [Golgi membrane] (R-HSA-157017) 18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [Golgi membrane] (R-HSA-1983676)	0.462	2
UniProt:Q9NZC7 WWOX	1	WWOX [cytosol] (R-HSA-1253335)	0.462	2
UniProt:P35613 BSG	2	BSG [plasma membrane] (R-HSA-197673) BSG [Golgi membrane] (R-HSA-204478)	0.462	2
UniProt:Q14677 CLINT1	1	CLINT1 [cytosol] (R-HSA-429811)	0.462	4
UniProt:Q14739 LBR	1	LBR [nuclear envelope] (R-HSA-194637)	0.462	2
UniProt:Q9H2J7 SLC6A15	1	SLC6A15 [plasma membrane] (R-HSA-352060)	0.462	4