DCP1-DCP2 complex decaps mRNA

Stable Identifier
R-HSA-429860
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The DCP1-DCP2 decapping complex binds the 7-methylguanosine cap of mRNA and hydrolyzes the triphosphate bond to yield 7-methylguanosine 5'-diphosphate and RNA with 5'-monophosphate. The DCP2 subunit of the complex catalyzes the hydrolysis. DCP2 has higher affinity for some subsets of mRNA.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
exoribonuclease activity, producing 5'-phosphomonoesters of DCP1-DCP2 Decapping Complex [cytosol]
Physical Entity
Activity
Orthologous Events