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CNOT7 [cytosol]
Stable Identifier
R-HSA-429877
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
CCR4-NOT transcription complex subunit 7, CNOT7_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Maternal to zygotic transition (MZT) (Homo sapiens)
M-decay: degradation of maternal mRNAs by maternally stored factors (Homo sapiens)
BTG4 binds CNOT7 of the CCR4-NOT complex, PABPN1L, and eIF4E of the mRNP (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT7 [cytosol] (Homo sapiens)
CCR4-NOT:BTG4:PABPN1L:mRNP [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT7 [cytosol] (Homo sapiens)
CCR4-NOT deadenylates mRNA in CCR4-NOT:BTG4:PABPN1L:mRNP (Homo sapiens)
CCR4-NOT:BTG4:PABPN1L:deadenylated mRNP [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT7 [cytosol] (Homo sapiens)
CCR4-NOT:BTG4:PABPN1L:mRNP [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT7 [cytosol] (Homo sapiens)
CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA (Homo sapiens)
CCR4-NOT(CNOT6L):ZFP36L2:deadenylated mRNA [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT7 or CNOT8 [cytosol] (Homo sapiens)
CNOT7 [cytosol] (Homo sapiens)
CCR4-NOT(CNOT6L):ZFP36L2:mRNA [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT7 or CNOT8 [cytosol] (Homo sapiens)
CNOT7 [cytosol] (Homo sapiens)
ZFP36L2 binds CNOT6L of CCR4-CNOT complex and an AU-rich element in mRNA (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT7 or CNOT8 [cytosol] (Homo sapiens)
CNOT7 [cytosol] (Homo sapiens)
CCR4-NOT(CNOT6L):ZFP36L2:mRNA [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT7 or CNOT8 [cytosol] (Homo sapiens)
CNOT7 [cytosol] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Homo sapiens)
BTG2 binds CCR4-NOT complex (Homo sapiens)
BTG2:CCR4-NOT [cytosol] (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT7 or CNOT8 [cytosol] (Homo sapiens)
CNOT7 [cytosol] (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT7 or CNOT8 [cytosol] (Homo sapiens)
CNOT7 [cytosol] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Deadenylation-dependent mRNA decay (Homo sapiens)
Deadenylation of mRNA (Homo sapiens)
CCR4-NOT complex deadenylates mRNA (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT7 or CNOT8 [cytosol] (Homo sapiens)
CNOT7 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UIV1 CNOT7
Gene Names
CNOT7, CAF1
Chain
chain:1-285
Reference Genes
BioGPS Gene:29883 CNOT7
COSMIC (genes):CNOT7 CNOT7
CTD Gene:29883 CNOT7
dbSNP Gene:29883 CNOT7
ENSEMBL:ENSG00000198791 CNOT7
HGNC:14101 CNOT7
KEGG:hsa:29883 CNOT7
Monarch:29883 CNOT7
NCBI Gene:29883 CNOT7
OMIM:604913 CNOT7
UCSC:Q9UIV1 CNOT7
Reference Transcript
RefSeq:NM_054026.3 CNOT7
RefSeq:NM_001322097.1 CNOT7
RefSeq:NM_001322087.1 CNOT7
RefSeq:NM_001322088.1 CNOT7
RefSeq:NM_013354.6 CNOT7
RefSeq:NM_001322089.1 CNOT7
RefSeq:NM_001322098.1 CNOT7
RefSeq:NM_001322100.1 CNOT7
RefSeq:NM_001322096.1 CNOT7
RefSeq:NM_001322093.1 CNOT7
RefSeq:XM_005273481.2 CNOT7
RefSeq:NM_001322091.1 CNOT7
RefSeq:NM_001322094.1 CNOT7
RefSeq:NM_001322092.1 CNOT7
RefSeq:NM_001322099.1 CNOT7
RefSeq:NM_001322095.1 CNOT7
RefSeq:NM_001322090.1 CNOT7
Other Identifiers
11718344_a_at
11718345_a_at
11718346_x_at
11733347_a_at
11733348_s_at
11750545_a_at
1552344_PM_s_at
1552344_s_at
218250_PM_s_at
218250_s_at
225053_PM_at
225053_at
233019_PM_at
233019_at
2353228
2353229
2353234
2729652
2729653
2729654
2729655
29883
3125768
3125770
3125772
3125774
3125776
3125777
3125778
3125779
3125780
3125781
3125782
3125783
3125784
3125785
3125786
3125787
3125788
3125789
3125792
3125793
3125794
3125795
3125796
3125797
3125798
3125799
3125800
3125801
3125803
3125805
3125806
3125807
3125808
3348183
4011557
4043224
4043227
45318_at
51523_at
65775_at
67499_at
73366_at
8149475
86691_at
A_23_P216312
A_23_P394166
A_32_P1144
A_32_P14737
A_32_P170888
GE493543
GE62980
GO:0000175
GO:0000288
GO:0000289
GO:0000290
GO:0000932
GO:0003676
GO:0003714
GO:0003723
GO:0003824
GO:0004527
GO:0004532
GO:0004535
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0006355
GO:0006402
GO:0006417
GO:0008284
GO:0008285
GO:0010629
GO:0016020
GO:0016071
GO:0016604
GO:0016607
GO:0016787
GO:0030014
GO:0030015
GO:0031047
GO:0033962
GO:0034584
GO:0035279
GO:0042509
GO:0043226
GO:0043232
GO:0045070
GO:0045892
GO:0045944
GO:0046872
GO:0051607
GO:0060090
GO:0060213
GO:0060339
GO:0061014
GO:0098542
GO:0140098
GO:0140110
GO:0140297
GO:0140991
GO:1900153
HMNXSV003031205
HMNXSV003057413
Hs.226318.1.A2_3p_at
Hs.287574.0.S1_3p_at
Hs2.380963.2.S1_3p_s_at
ILMN_1656134
ILMN_1686477
ILMN_1715886
PH_hs_0017219
PH_hs_0022814
TC08001011.hg
g10518495_3p_s_at
p28431
Participates
as a component of
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
as a member of
CNOT7 or CNOT8 [cytosol] (Homo sapiens)
Inferred To
Cnot7 [cytosol]
(Mus musculus)
CNOT7 [cytosol]
(Bos taurus)
CNOT7 [cytosol]
(Canis familiaris)
CNOT7 [cytosol]
(Danio rerio)
CNOT7 [cytosol]
(Dictyostelium discoideum)
CNOT7 [cytosol]
(Gallus gallus)
CNOT7 [cytosol]
(Rattus norvegicus)
CNOT7 [cytosol]
(Sus scrofa)
CNOT7 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_473367.2
,
NP_001309016.1
,
NP_001309024.1
,
XP_005273538.1
,
NP_001309026.1
,
NP_001309025.1
,
NP_001309028.1
,
NP_001309020.1
,
NP_037486.2
,
NP_001309021.1
,
NP_001309017.1
,
NP_001309027.1
,
NP_001309022.1
,
NP_001309018.1
,
NP_001309029.1
,
NP_001309019.1
,
NP_001309023.1
OpenTargets
ENSG00000198791
ENSEMBL
ENSP00000429093
,
ENST00000523917
,
ENSP00000355279
,
ENST00000361272
HPA
ENSG00000198791-CNOT7
PRO
Q9UIV1
Pharos - Targets
Q9UIV1
GlyGen
Q9UIV1
PDB
2D5R
,
4GMJ
,
7AX1
,
7VOI
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P78543 BTG2
1
BTG2 [cytosol]
(R-HSA-6798008)
0.798
8
UniProt:P62324 BTG1
1
BTG1 [nucleoplasm]
(R-HSA-9620886)
0.721
4
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
13
UniProt:Q9UKV8 AGO2
2
AGO2 [cytosol]
(R-HSA-209723)
AGO2 [nucleoplasm]
(R-HSA-5578701)
0.564
2
UniProt:Q92600 RQCD1
2
RQCD1 [nucleoplasm]
(R-HSA-6810130)
RQCD1 [cytosol]
(R-HSA-430029)
0.527
2
UniProt:P47756 CAPZB
1
CAPZB [cytosol]
(R-HSA-879409)
0.527
3
UniProt:P09237 MMP7
6
MMP7(18-267) [extracellular region]
(R-HSA-1604734)
MMP7(51-267) [extracellular region]
(R-HSA-1604766)
MMP7(18-50) [extracellular region]
(R-HSA-1604759)
MMP7(51-94) [extracellular region]
(R-HSA-1604760)
MMP7(95-267) [extracellular region]
(R-HSA-1442479)
MMP7(18-94) [extracellular region]
(R-HSA-1604729)
0.527
3
UniProt:P22893
2
phospho-Zfp36 [cytosol]
(R-MMU-450496)
Zfp36 [cytosol]
(R-MMU-450562)
0.499
3
UniProt:P42224 STAT1
8
STAT1 [cytosol]
(R-HSA-629622)
p-Y701-STAT1 [cytosol]
(R-HSA-3132766)
p-Y701-STAT1 [nucleoplasm]
(R-HSA-6788624)
p-Y701-STAT1 [cytosol]
(R-HSA-8951202)
p-Y701-STAT1 [nucleoplasm]
(R-HSA-8985905)
p-Y701,S727-STAT1 [cytosol]
(R-HSA-9850842)
p-STAT1 [cytosol]
(R-HSA-8950418)
p-STAT1 [nucleoplasm]
(R-HSA-8987140)
0.463
2
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