Reactome | DCP1A [cytosol]

DCP1A [cytosol]

Stable Identifier

R-HSA-430043

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

mRNA-decapping enzyme 1A, DCP1A_HUMAN

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External Reference Information

External Reference

UniProt:Q9NPI6 DCP1A

Gene Names

DCP1A, SMIF

Chain

chain:1-582

Reference Genes

BioGPS Gene:55802 DCP1A

COSMIC (genes):DCP1A DCP1A

CTD Gene:55802 DCP1A

dbSNP Gene:55802 DCP1A

ENSEMBL:ENSG00000272886 DCP1A

HGNC:18714 DCP1A

KEGG Gene (Homo sapiens):55802 DCP1A

Monarch:55802 DCP1A

NCBI Gene:55802 DCP1A

OMIM:607010 DCP1A

UCSC:Q9NPI6 DCP1A

Reference Transcript

Other Identifiers

0006660358

11719470_a_at

11719471_at

16955096

16955098

218508_at

225443_at

2676718

2676719

2676720

2676721

2676722

2676723

2676725

2676727

2676728

2676731

2676732

2676733

2676736

2676738

2676747

2676749

2676751

2676759

2676760

2676761

2676762

2676763

44124_at

46655_at

47513_at

55802

8088126

8088128

A_23_P166826

A_24_P576174

GE55320

GE62764

GE87987

GO:0000184

GO:0000290

GO:0000932

GO:0003674

GO:0003723

GO:0003729

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005737

GO:0005829

GO:0008047

GO:0008092

GO:0008150

GO:0009056

GO:0016020

GO:0016787

GO:0019894

GO:0030234

GO:0031087

GO:0034641

GO:0034655

GO:0036464

GO:0042802

GO:0043085

GO:0043226

GO:0043488

GO:0043928

GO:1903608

Hs.141003.0.S1_3p_at

ILMN_1809285

PH_hs_0008362

PH_hs_0024135

TC03001467.hg

TC03001468.hg

TC03002920.hg

g8923766_3p_at

Participant Of

hasComponent

input

Inferred To

DCP1 [cytosol] (Drosophila melanogaster)

DCP1 [cytosol] (Saccharomyces cerevisiae)

dcap-1 [cytosol] (Caenorhabditis elegans)

dcp1a [cytosol] (Danio rerio)

dcp1a [cytosol] (Xenopus tropicalis)

DCP1A [cytosol] (Bos taurus)

DCP1A [cytosol] (Canis familiaris)

DCP1A [cytosol] (Dictyostelium discoideum)

DCP1A [cytosol] (Gallus gallus)

DCP1A [cytosol] (Plasmodium falciparum)

DCP1A [cytosol] (Sus scrofa)

Dcp1a [cytosol] (Mus musculus)

Dcp1a [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_060873.4, NP_001277136.1, NP_001277134.1, NP_001277133.1, NP_001277135.1

OpenTargets

ENSG00000272886

HPA

ENSG00000272886-DCP1A

GeneCards

Q9NPI6

Ensembl

ENST00000294241, ENST00000610213, ENSG00000272886, ENSP00000476386, ENSP00000476046

PRO

Q9NPI6

PDB

2WX3, 4B6H

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96F86 EDC3	1	EDC3 [cytosol] (R-HSA-429997)	0.937	14
UniProt:Q8IU60 DCP2	1	DCP2 [cytosol] (R-HSA-429937)	0.908	10
UniProt:P26196 DDX6	1	DDX6 [cytosol] (R-HSA-430032)	0.842	8
UniProt:Q9NPJ4 PNRC2	1	PNRC2 [cytosol] (R-HSA-8879146)	0.837	10
UniProt:Q6P2E9 EDC4	1	EDC4 [cytosol] (R-HSA-429963)	0.787	10
UniProt:Q92900 UPF1	2	p-4S-UPF1 [cytosol] (R-HSA-927856) UPF1 [cytosol] (R-HSA-927734)	0.783	13
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.781	10
UniProt:Q13485 SMAD4	88	SMAD4 K428T [cytosol] (R-HSA-3311004) SMAD4 P356R [cytosol] (R-HSA-3310988) SMAD4 D351del [cytosol] (R-HSA-3310974) SMAD4 R361H [cytosol] (R-HSA-3310984) SMAD4 P356L [cytosol] (R-HSA-3310987) SMAD4 A406T [cytosol] (R-HSA-3311003) SMAD4 D351Y [cytosol] (R-HSA-3310970) SMAD4 D351H [cytosol] (R-HSA-3310965) SMAD4 R361C [cytosol] (R-HSA-3310983) SMAD4 D351G [cytosol] (R-HSA-3310967) SMAD4 R515T [cytosol] (R-HSA-3311008) SMAD4 G352* [cytosol] (R-HSA-9678445) SMAD4 S178* [cytosol] (R-HSA-9675630) SMAD4 G477* [cytosol] (R-HSA-9678447) SMAD4 G473* [cytosol] (R-HSA-9678440) SMAD4 S144* [cytosol] (R-HSA-9675625) SMAD4 E538* [cytosol] (R-HSA-9675626) SMAD4 E390* [cytosol] (R-HSA-9675620) SMAD4 S154* [cytosol] (R-HSA-9675621) SMAD4 E330* [cytosol] (R-HSA-9675622) SMAD4 E417* [cytosol] (R-HSA-9675623) SMAD4 Y195* [cytosol] (R-HSA-9678462) SMAD4 E108* [cytosol] (R-HSA-9675640) SMAD4 S343* [cytosol] (R-HSA-9675641) SMAD4 E520* [cytosol] (R-HSA-9675636) SMAD4 G510* [cytosol] (R-HSA-9678452) SMAD4 G358* [cytosol] (R-HSA-9678453) SMAD4 E175* [cytosol] (R-HSA-9675637) SMAD4 E307* [cytosol] (R-HSA-9675639) SMAD4 E53* [cytosol] (R-HSA-9675633) SMAD4 S171* [cytosol] (R-HSA-9675634) SMAD4 G30* [cytosol] (R-HSA-9678450) SMAD4 G168* [cytosol] (R-HSA-9678451) SMAD4 Q366* [cytosol] (R-HSA-9675200) SMAD4 R135* [cytosol] (R-HSA-9675090) SMAD4 L146* [cytosol] (R-HSA-9678509) SMAD4 L440* [cytosol] (R-HSA-9678510) SMAD4 Q183* [cytosol] (R-HSA-9675176) SMAD4 Q289* [cytosol] (R-HSA-9675177) SMAD4 Q248* [cytosol] (R-HSA-9675178) SMAD4 Q249* [cytosol] (R-HSA-9675172) SMAD4 Q256* [cytosol] (R-HSA-9675173) SMAD4 Q239* [cytosol] (R-HSA-9675174) SMAD4 Q245* [cytosol] (R-HSA-9675175) SMAD4 Q224* [cytosol] (R-HSA-9675168) SMAD4 W509* [cytosol] (R-HSA-9678497) SMAD4 Q311* [cytosol] (R-HSA-9675169) SMAD4 W398* [cytosol] (R-HSA-9678498) SMAD4 Q250* [cytosol] (R-HSA-9675170) SMAD4 Q410* [cytosol] (R-HSA-9675196) SMAD4 Q534* [cytosol] (R-HSA-9675197) SMAD4 Q83* [cytosol] (R-HSA-9675199) SMAD4 Q448* [cytosol] (R-HSA-9675192) SMAD4 K428R [cytosol] (R-HSA-3311001) SMAD4 Q455* [cytosol] (R-HSA-9675193) SMAD4 R445* [cytosol] (R-HSA-9675065) SMAD4 Q442* [cytosol] (R-HSA-9675194) SMAD4 Q516* [cytosol] (R-HSA-9675195) SMAD4 C443* [cytosol] (R-HSA-9678523) SMAD4 Q334* [cytosol] (R-HSA-9675191) SMAD4 R361G [cytosol] (R-HSA-3310993) SMAD4 L172* [cytosol] (R-HSA-9678514) SMAD4 K122* [cytosol] (R-HSA-9678515) SMAD4 R361S [cytosol] (R-HSA-3310994) SMAD4 Y430* [cytosol] (R-HSA-9678476) SMAD4 Y260* [cytosol] (R-HSA-9678477) SMAD4 Y95* [cytosol] (R-HSA-9678478) SMAD4 Y322* [cytosol] (R-HSA-9678479) SMAD4 E321* [cytosol] (R-HSA-9675658) SMAD4 Y412* [cytosol] (R-HSA-9678469) SMAD4 R515* [cytosol] (R-HSA-3311012) SMAD4 Y328* [cytosol] (R-HSA-9678470) SMAD4 E33* [cytosol] (R-HSA-9675654) SMAD4 Y513* [cytosol] (R-HSA-9678471) SMAD4 E526* [cytosol] (R-HSA-9675648) SMAD4 S138* [cytosol] (R-HSA-9675649) SMAD4 Y276* [cytosol] (R-HSA-9678466) SMAD4 E205* [cytosol] (R-HSA-9675650) SMAD4 E49* [cytosol] (R-HSA-9675651) SMAD4 W101* [cytosol] (R-HSA-9678492) SMAD4 W268* [cytosol] (R-HSA-9678494) SMAD4 [nucleoplasm] (R-HSA-177103) SMAD4 [cytosol] (R-HSA-170862) RibC-SMAD4 [nucleoplasm] (R-HSA-2187323) SMAD4 W524* [cytosol] (R-HSA-9678491) SMAD4 W302* [cytosol] (R-HSA-9678490) SMAD4 S242* [cytosol] (R-HSA-9675167) SMAD4 Q116* [cytosol] (R-HSA-9675166)	0.779	5
UniProt:Q9NPI6 DCP1A	1	DCP1A [cytosol] (R-HSA-430043)	0.761	9
UniProt:O95429 BAG4	3	BAG4(1-126):p-8Y FGFR1(208-822) fusion [plasma membrane] (R-HSA-8853156) BAG4 [cytosol] (R-HSA-5212670) BAG4(1-126):FGFR1(208-822) fusion [plasma membrane] (R-HSA-8853157)	0.728	5
UniProt:Q8IZD4 DCP1B	1	DCP1B [cytosol] (R-HSA-429834)	0.695	8
UniProt:Q9NPJ4-1 PNRC2			0.671	6
UniProt:Q96K30 RITA1			0.666	4
UniProt:Q3E7X9 RPS28A	1	RPS28A [cytosol] (R-SCE-9633107)	0.556	3
UniProt:P43351 RAD52	3	p-Y104-RAD52 [nucleoplasm] (R-HSA-5686588) SUMO1-K411,K412,K414-RAD52 [nucleoplasm] (R-HSA-4568909) RAD52 [nucleoplasm] (R-HSA-62639)	0.556	5
UniProt:Q8IU60-2 DCP2			0.527	2
UniProt:Q92636 NSMAF	1	NSMAF [cytosol] (R-HSA-5626992)	0.527	2
UniProt:F4HZB2 BCHA1			0.527	2
UniProt:Q12796 PNRC1			0.527	2
UniProt:P26651 ZFP36	2	ZFP36 [cytosol] (R-HSA-450562) p-S60,S186-ZFP36 [cytosol] (R-HSA-450496)	0.499	2

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