Reactome | DCX [cytosol]

DCX [cytosol]

Stable Identifier

R-HSA-430060

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Doublecortin, Neuronal migration protein doublecortin, DCX_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43602 DCX

Gene Names

DCX, DBCN, LISX

Chain

chain:1-365

Reference Genes

BioGPS Gene:1641 DCX

COSMIC (genes):DCX DCX

CTD Gene:1641 DCX

dbSNP Gene:1641 DCX

ENSEMBL:ENSG00000077279 DCX

HGNC:2714 DCX

KEGG:hsa:1641 DCX

Monarch:1641 DCX

NCBI Gene:1641 DCX

OMIM:300121 DCX

UCSC:O43602 DCX

Reference Transcript

Participates

as a component of

as an input of

Cross References

RefSeq

NP_000546.2, NP_835364.1, NP_835366.1, NP_835365.1, NP_001356300.1

OpenTargets

ENSG00000077279

ENSEMBL

ENSG00000077279, ENST00000635795, ENSP00000489635, ENST00000488120, ENSP00000419861

HPA

ENSG00000077279-DCX

GeneCards

DCX

PRO

O43602

Pharos - Targets

O43602

Orphanet

DCX

HMDB Protein

HMDBP07647

PDB

5IO9, 6FNZ, 5IN7, 6RFD, 4ATU, 6RF8, 5IP4, 5IOI, 2XRP, 5IKC, 6REV, 1MJD, 6RF2, 2BQQ

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13422 IKZF1			0.666	4
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.666	4
UniProt:O15062 ZBTB5			0.666	4
UniProt:Q6NUQ1 RINT1	1	RINT1 [cytosol] (R-HSA-6810991)	0.666	4
UniProt:Q13137 CACO2			0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.556	3
UniProt:P50221 MEOX1			0.556	3
UniProt:Q9UJV3-2 MID2			0.556	3
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.556	3
UniProt:P36406 TRI23			0.556	3
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	3
UniProt:Q9BVG8 KIFC3			0.556	3
UniProt:Q96R06 SPAG5			0.556	3
UniProt:Q96PV0 SYNGAP1	1	SYNGAP1 [cytosol] (R-HSA-5658217)	0.527	4
UniProt:O15075 DCLK1			0.527	3
UniProt:Q9BSI4 TINF2	1	TINF2 [nucleoplasm] (R-HSA-174883)	0.508	2
UniProt:Q9BSE5 AGMAT	1	AGMAT(1-?) [mitochondrion] (R-HSA-350595)	0.499	2

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