PARVB interacts with Alpha-actinin

Stable Identifier
R-HSA-430308
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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PARVB interacts with the actin cross-linking protein Alpha-actinin (Yamaji et al. 2004). The ILK-PARVB complex may serve as an integrin-anchoring site for alpha-actinin and thereby mediate integrin signaling to alpha-actinin, which has been shown to play an important role in actin polymerization at focal adhesions (Yamaji et al., 2004).

Literature References
PubMed ID Title Journal Year
15159419 Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction

Yamaji, S, Suzuki, A, Kanamori, H, Mishima, W, Yoshimi, R, Takasaki, H, Takabayashi, M, Fujimaki, K, Fujisawa, S, Ohno, S, Ishigatsubo, Y

J Cell Biol 2004
Participants
Participant Of
Orthologous Events
Authored
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Created