Mig-2 recruits Migfilin to the cell-ECM adhesions

Stable Identifier
R-HSA-430341
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Migfilin functions in cell shape modulation regulating filamin-mediated cross-linking and stabilization of actin filaments. Migfilin is recruited to cell–Extra Cellular Matrix adhesion sites in a variety of fibroblasts, epithelial, and endothelial cells by interaction with Mig-2 (Tu et al., 2003).

Literature References
PubMed ID Title Journal Year
12679033 Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation

Tu, Y, Wu, S, Shi, X, Chen, K, Wu, C

Cell 2003
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created