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p-T287-CAMK2D [plasma membrane]
Stable Identifier
R-HSA-432794
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Ca/Calmodulin dependent protein kinase II delta subunit
Locations in the PathwayBrowser
Expand all
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Ion homeostasis (Homo sapiens)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Homo sapiens)
CAMK2 heteromer:CALM:4xCa2+ [plasma membrane] (Homo sapiens)
CAMK2 heteromer [plasma membrane] (Homo sapiens)
p-CAMK2D, p-CAMK2G [plasma membrane] (Homo sapiens)
p-T287-CAMK2D [plasma membrane] (Homo sapiens)
Phase 0 - rapid depolarisation (Homo sapiens)
SCNAs:SNCBs transport Na+ from extracellular region to cytosol (Homo sapiens)
CAMK2 heteromer:CALM:4xCa2+ [plasma membrane] (Homo sapiens)
CAMK2 heteromer [plasma membrane] (Homo sapiens)
p-CAMK2D, p-CAMK2G [plasma membrane] (Homo sapiens)
p-T287-CAMK2D [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Ion transport by P-type ATPases (Homo sapiens)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Homo sapiens)
CAMK2 heteromer:CALM:4xCa2+ [plasma membrane] (Homo sapiens)
CAMK2 heteromer [plasma membrane] (Homo sapiens)
p-CAMK2D, p-CAMK2G [plasma membrane] (Homo sapiens)
p-T287-CAMK2D [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13557 CAMK2D
Gene Names
CAMK2D, CAMKD
Chain
initiator methionine:, chain:2-499
Reference Genes
BioGPS Gene:817 CAMK2D
COSMIC (genes):CAMK2D CAMK2D
CTD Gene:817 CAMK2D
dbSNP Gene:817 CAMK2D
ENSEMBL:ENSG00000145349 CAMK2D
ENSEMBL_homo_sapiens_GENE:ENSG00000145349.20 CAMK2D
HGNC:1462 CAMK2D
KEGG Gene (Homo sapiens):817 CAMK2D
Monarch:817 CAMK2D
NCBI Gene:817 CAMK2D
OMIM:607708 CAMK2D
UCSC:Q13557 CAMK2D
Reference Transcript
RefSeq:NM_001321589.1 CAMK2D
RefSeq:XM_011532291.1 CAMK2D
RefSeq:NM_001321566.1 CAMK2D
RefSeq:NM_172129.1 CAMK2D
RefSeq:NM_172115.2 CAMK2D
RefSeq:XM_011532289.1 CAMK2D
RefSeq:NM_172128.2 CAMK2D
RefSeq:NM_001221.3 CAMK2D
RefSeq:NM_172114.1 CAMK2D
RefSeq:NM_001321580.1 CAMK2D
RefSeq:NM_172127.2 CAMK2D
RefSeq:NM_001321573.1 CAMK2D
Other Identifiers
11725326_a_at
11725327_a_at
11740063_a_at
11746540_a_at
16979133
224994_PM_at
224994_at
225019_PM_at
225019_at
228555_PM_at
228555_at
231793_PM_s_at
231793_s_at
2782536
2782544
2782546
2782547
2782548
2782549
2782550
2782551
2782552
2782553
2782554
2782555
2782556
2782557
2782559
2782561
2782579
2782582
2782588
2782591
2782592
2782594
2782597
2782602
2782604
2782614
2782618
2782627
2782634
2782660
2782662
2782663
2782664
2782665
2782666
2782667
2782668
2782669
44603_at
56458_at
78436_at
8102415
817
A_23_P144458
A_24_P106166
A_24_P114739
A_32_P47988
GE62184
GO:0000166
GO:0001558
GO:0002026
GO:0003012
GO:0003013
GO:0003254
GO:0003824
GO:0004672
GO:0004674
GO:0004683
GO:0005515
GO:0005516
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005829
GO:0005886
GO:0005954
GO:0006351
GO:0006355
GO:0006357
GO:0006468
GO:0008016
GO:0008092
GO:0010613
GO:0010649
GO:0010666
GO:0010880
GO:0010881
GO:0012501
GO:0016020
GO:0016301
GO:0016310
GO:0016529
GO:0016740
GO:0018105
GO:0018107
GO:0019871
GO:0023052
GO:0030666
GO:0031410
GO:0031432
GO:0032469
GO:0033017
GO:0036211
GO:0042383
GO:0042802
GO:0042803
GO:0043005
GO:0043226
GO:0044325
GO:0046777
GO:0055065
GO:0055085
GO:0055119
GO:0060314
GO:0060341
GO:0071277
GO:0086003
GO:0086091
GO:0098772
GO:0098901
GO:0098909
GO:0106310
GO:0140096
GO:1901844
GO:1901897
GO:1902306
GO:1902514
GO:2000650
HMNXSV003014371
HMNXSV003037228
Hs.111460.0.A1_3p_at
Hs.111460.0.A2_3p_at
Hs.111460.0.A2_3p_x_at
Hs.111460.3.S2_3p_a_at
Hs.32553.0.A1_3p_at
ILMN_1658818
ILMN_1683415
ILMN_1757060
ILMN_2319544
PH_hs_0006117
TC04001486.hg
TC04002680.hg
U50361_s_at
U73738_at
Participates
as a member of
p-CAMK2D, p-CAMK2G [plasma membrane] (Homo sapiens)
Other forms of this molecule
p-T287-CAMK2D [nucleoplasm]
p-T287-CAMK2D [endocytic vesicle membrane]
CAMK2D [cytosol]
p-T287-CAMK2D [cytosol]
Inferred To
phospho-p-T287-CAMK2D [plasma membrane]
(Bos taurus)
phospho-p-T287-CAMK2D [plasma membrane]
(Caenorhabditis elegans)
phospho-p-T287-CAMK2D [plasma membrane]
(Drosophila melanogaster)
phospho-p-T287-CAMK2D [plasma membrane]
(Gallus gallus)
phospho-p-T287-CAMK2D [plasma membrane]
(Mus musculus)
phospho-p-T287-CAMK2D [plasma membrane]
(Plasmodium falciparum)
phospho-p-T287-CAMK2D [plasma membrane]
(Rattus norvegicus)
phospho-p-T287-CAMK2D [plasma membrane]
(Sus scrofa)
Modified Residues
Name
O-phospho-L-threonine at 287
Coordinate
287
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_001308518.1
,
NP_001308495.1
,
NP_742127.1
,
NP_001308502.1
,
NP_742126.1
,
NP_742125.1
,
NP_742113.1
,
NP_742112.1
,
NP_001212.2
,
XP_011530591.1
,
XP_011530593.1
,
NP_001308509.1
ZINC - World Drugs
KCC2D_HUMAN
Guide to Pharmacology - Targets
1558
OpenTargets
ENSG00000145349
ZINC - FDA approved
KCC2D_HUMAN
ZINC - Substances
KCC2D_HUMAN
ZINC - Biogenic
KCC2D_HUMAN
ZINC target
Q13557
PRO
Q13557
PDB
2W2C
,
7ZRQ
,
7ZRP
,
5VLO
,
3GP2
,
6AYW
,
2WEL
,
2VN9
ZINC - Investigational
KCC2D_HUMAN
HPA
ENSG00000145349-CAMK2D
GeneCards
Q13557
Ensembl
ENST00000699047
,
ENST00000699048
,
ENSP00000296402
,
ENST00000342666
,
ENST00000394524
,
ENSP00000369098
,
ENST00000683023
,
ENST00000394522
,
ENSP00000514099
,
ENST00000515496
,
ENST00000296402
,
ENST00000699381
,
ENSP00000514100
,
ENSP00000423482
,
ENSP00000339740
,
ENST00000379773
,
ENST00000508738
,
ENSP00000514346
,
ENSP00000378030
,
ENSP00000422566
,
ENSG00000145349
,
ENSP00000378032
,
ENSP00000507073
Pharos - Targets
Q13557
ZINC - Predictions - Purchasable
KCC2D_HUMAN
Orphanet
27552
HMDB Protein
HMDBP01469
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8N9N5 BANP
1
BANP [nucleoplasm]
(R-HSA-3221973)
0.666
4
UniProt:Q8N0Z6 TTC5
3
TTC5 [nucleoplasm]
(R-HSA-6804264)
p-S203-TTC5 [nucleoplasm]
(R-HSA-6804261)
p-S203,S221-TTC5 [nucleoplasm]
(R-HSA-6804259)
0.666
4
UniProt:O96015 DNAL4
1
DNAL4 [plasma membrane]
(R-HSA-177484)
0.666
4
UniProt:Q96PM5 RCHY1
2
RCHY1 [cytosol]
(R-HSA-976013)
RCHY1 [nucleoplasm]
(R-HSA-5655134)
0.499
2
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