Reactome | LIMS1 [cytosol]

LIMS1 [cytosol]

Stable Identifier

R-HSA-432859

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

PINCH1, LIM and senescent cell antigen-like-containing domain protein 1, LIMS1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9Y623 MYH4

Expand all

External Reference Information

External Reference

UniProt:P48059 LIMS1

Gene Names

LIMS1, PINCH, PINCH1

Chain

initiator methionine:, chain:2-325

Reference Genes

BioGPS Gene:3987 LIMS1

COSMIC (genes):LIMS1 LIMS1

CTD Gene:3987 LIMS1

dbSNP Gene:3987 LIMS1

ENSEMBL:ENSG00000169756 LIMS1

HGNC:6616 LIMS1

KEGG:hsa:3987 LIMS1

Monarch:3987 LIMS1

NCBI Gene:3987 LIMS1

OMIM:602567 LIMS1

UCSC:P48059 LIMS1

Reference Transcript

Participates

as a component of

Rsu-1:Pinch1 complex [cytosol] (Homo sapiens)

as an input of

Rsu-1 interacts with Pinch1 (Homo sapiens)

as a member of

PINCH [cytosol] (Homo sapiens)

as a candidate of

PINCH [cytosol] (Homo sapiens)

Inferred To

LIMS1 [cytosol] (Bos taurus)

LIMS1 [cytosol] (Canis familiaris)

LIMS1 [cytosol] (Dictyostelium discoideum)

LIMS1 [cytosol] (Gallus gallus)

LIMS1 [cytosol] (Sus scrofa)

unc-97 [cytosol] (Caenorhabditis elegans)

Lims1 [cytosol] (Mus musculus)

Lims1 [cytosol] (Rattus norvegicus)

stck [cytosol] (Drosophila melanogaster)

Cross References

OpenTargets

ENSG00000169756

ENSEMBL

ENST00000695518, ENSP00000337598, ENSG00000169756, ENSP00000387264, ENSP00000331775, ENST00000409441, ENSP00000386926, ENSP00000437912, ENST00000695521, ENSP00000376987, ENST00000410093, ENST00000393310, ENST00000332345, ENST00000338045, ENSP00000511984, ENST00000544547, ENSP00000511981

HPA

ENSG00000169756-LIMS1

GeneCards

LIMS1

PRO

P48059

Pharos - Targets

P48059

GlyGen

P48059

PDB

2KBX, 7D2S, 2COR, 7D2U, 3F6Q, 2D8X, 1NYP, 6MIF, 1U5S, 7D2T, 7LT9, 1G47, 4HI9, 4HI8

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13418 ILK	1	ILK [cytosol] (R-HSA-432864)	0.961	18
UniProt:Q15404 RSU1	1	RSU1 [cytosol] (R-HSA-446297)	0.848	8
UniProt:O55222	1	ILK [cytosol] (R-MMU-432864)	0.713	4
UniProt:Q9NVD7 PARVA	1	PARVA [cytosol] (R-HSA-432848)	0.643	4
UniProt:O43639 NCK2	1	NCK2 [cytosol] (R-HSA-204885)	0.623	2
UniProt:P09022 Hoxa1	1	Hoxa1 [nucleoplasm] (R-MMU-5617924)	0.57	3
UniProt:Q99708 RBBP8	4	p-S327,T847,T859-RBBP8 [nucleoplasm] (R-HSA-5684138) Ac-K-RBBP8 [nucleoplasm] (R-HSA-5685955) RBBP8 [nucleoplasm] (R-HSA-912399) p-S327,T847-RBBP8 [nucleoplasm] (R-HSA-5684083)	0.553	2
UniProt:Q9HBI0 PARVG			0.527	3
UniProt:Q15654 TRIP6			0.527	2
UniProt:Q9HBI1 PARVB	1	PARVB [cytosol] (R-HSA-446016)	0.527	3
UniProt:P04818 TYMS	1	TYMS [cytosol] (R-HSA-73518)	0.527	2
UniProt:Q9Y623 MYH4			0.527	2
UniProt:Q9Y3P9 RABGAP1	1	RABGAP1 [cytosol] (R-HSA-8854144)	0.527	2
UniProt:Q8NFW8 CMAS	1	CMAS [nucleoplasm] (R-HSA-4085417)	0.527	3
UniProt:Q9NS73 MBIP	1	MBIP [nucleoplasm] (R-HSA-3662291)	0.488	2

Cite Us!