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Nucleosome with H3K27me3 [nucleoplasm]
Stable Identifier
R-HSA-433757
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Nucleosome with H3 Trimethylated at Lysine-27
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
Oxidative Stress Induced Senescence (Homo sapiens)
Demethylation of H3K27Me3 by KDM6B stimulates p16INK4A transcription, while binding of PRC1.4 complex to H3K27Me3 represses p16INK4A transcription (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
KDM6B demethylates H3K27me3 on p16INK4A promoter (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
p-MAPKAPK3 phosphorylates BMI1 (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
PRC2 methylates histones and DNA (Homo sapiens)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Homo sapiens)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Homo sapiens)
PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] (Homo sapiens)
Chromatin with hemimethylC, H3K27me3 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
PRC2 trimethylates histone H3 at lysine-27 (Homo sapiens)
PRC2:Chromatin (H3K27me3) [nucleoplasm] (Homo sapiens)
Chromatin with trimethylated H3K27 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Participants
components
x 2
HIST1H4 [nucleoplasm]
(Homo sapiens)
x 2
Histone H2A [nucleoplasm]
(Homo sapiens)
x 2
Histone H2B [nucleoplasm]
(Homo sapiens)
x 2
Histone H3 (H3K27me3) [nucleoplasm]
(Homo sapiens)
Participates
as a component of
Chromatin with hemimethylC, H3K27me3 [nucleoplasm] (Homo sapiens)
Chromatin with trimethylated H3K27 [nucleoplasm] (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Inferred To
Nucleosome with H3K27me3 [nucleoplasm]
(Bos taurus)
Nucleosome with H3K27me3 [nucleoplasm]
(Caenorhabditis elegans)
Nucleosome with H3K27me3 [nucleoplasm]
(Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm]
(Danio rerio)
Nucleosome with H3K27me3 [nucleoplasm]
(Dictyostelium discoideum)
Nucleosome with H3K27me3 [nucleoplasm]
(Drosophila melanogaster)
Nucleosome with H3K27me3 [nucleoplasm]
(Gallus gallus)
Nucleosome with H3K27me3 [nucleoplasm]
(Mus musculus)
Nucleosome with H3K27me3 [nucleoplasm]
(Plasmodium falciparum)
Nucleosome with H3K27me3 [nucleoplasm]
(Rattus norvegicus)
Nucleosome with H3K27me3 [nucleoplasm]
(Saccharomyces cerevisiae)
Nucleosome with H3K27me3 [nucleoplasm]
(Schizosaccharomyces pombe)
Nucleosome with H3K27me3 [nucleoplasm]
(Sus scrofa)
Nucleosome with H3K27me3 [nucleoplasm]
(Xenopus tropicalis)
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