Reactome | AP3B1 [cytoplasmic vesicle membrane]

AP3B1 [cytoplasmic vesicle membrane]

Stable Identifier

R-HSA-434197

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytoplasmic vesicle membrane

Synonyms

AP-3 complex subunit beta-1, AP3B1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O00203 AP3B1

Gene Names

AP3B1, ADTB3A

Chain

chain:1-1094

Reference Genes

BioGPS Gene:8546 AP3B1

COSMIC (genes):AP3B1 AP3B1

CTD Gene:8546 AP3B1

dbSNP Gene:8546 AP3B1

ENSEMBL:ENSG00000132842 AP3B1

HGNC:566 AP3B1

KEGG:hsa:8546 AP3B1

Monarch:8546 AP3B1

NCBI Gene:8546 AP3B1

OMIM:603401 AP3B1

UCSC:O00203 AP3B1

Reference Transcript

Participates

as a candidate of

Golgi-associated Vesicle Cargo [cytoplasmic vesicle membrane] (Homo sapiens)

Other forms of this molecule

AP3B1 [Golgi membrane]

AP3B1(1-859)-BRAF(381-766) fusion [cytosol]

AP3B1(1-859)-p-BRAF(381-766) fusion [cytosol]

Inferred To

AP3B1 [cytoplasmic vesicle membrane] (Bos taurus)

AP3B1 [cytoplasmic vesicle membrane] (Canis familiaris)

AP3B1 [cytoplasmic vesicle membrane] (Gallus gallus)

AP3B1 [cytoplasmic vesicle membrane] (Sus scrofa)

Ap3b1 [cytoplasmic vesicle membrane] (Mus musculus)

Ap3b1 [cytoplasmic vesicle membrane] (Rattus norvegicus)

rb [cytoplasmic vesicle membrane] (Drosophila melanogaster)

APL6 [cytoplasmic vesicle membrane] (Saccharomyces cerevisiae)

ap3b-2 [cytoplasmic vesicle membrane] (Dictyostelium discoideum)

apb-3 [cytoplasmic vesicle membrane] (Caenorhabditis elegans)

Cross References

ENSEMBL

ENST00000255194, ENST00000519295, ENSP00000430597, ENSP00000255194, ENSG00000132842

OpenTargets

ENSG00000132842

GeneCards

AP3B1

HPA

ENSG00000132842-AP3B1

PRO

O00203

Pharos - Targets

O00203

GlyGen

O00203

Orphanet

AP3B1

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.564	2
UniProt:P37840 SNCA	5	SNCA [cytosol] (R-HSA-5658500) p-S129-SNCA [cytosol] (R-HSA-9836432) Ub-SNCA [cytosol] (R-HSA-5660754) SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	6
UniProt:Q96CV9 OPTN	6	p-S177,S473,S513-OPTN [cytosol] (R-HSA-9687840) OPTN [cytosol] (R-HSA-9687907) p-S177-OPTN [cytosol] (R-HSA-2562525) p-S177-OPTN [nucleoplasm] (R-HSA-2562595) OPTN [Golgi membrane] (R-HSA-2161111) OPTN [recycling endosome membrane] (R-HSA-8854141)	0.556	3
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.527	2
UniProt:P0DTC4 E	9	Ub-3xPalmC-E [virion membrane] (R-COV-9698416) Ub-3xPalmC-E [endocytic vesicle membrane] (R-COV-9698422) Ub-3xPalmC-E [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698420) Ub-3xPalmC-E [Golgi membrane] (R-COV-9694687) Ub-3xPalmC-E [endoplasmic reticulum membrane] (R-COV-9694465) Ub-3xPalmC-E [endoplasmic reticulum lumen] (R-COV-9694423) 3xPalmC-E [endoplasmic reticulum lumen] (R-COV-9694305) nascent E [endoplasmic reticulum lumen] (R-COV-9694312) N-glycan E [endoplasmic reticulum lumen] (R-COV-9694754)	0.527	2

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