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TGOLN2 [Golgi membrane]
Stable Identifier
R-HSA-434342
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Trans-Golgi network integral membrane protein 2, TGON2_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Golgi Associated Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
TGOLN2 [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
TGOLN2 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Coat Assembly (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
TGOLN2 [Golgi membrane] (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
TGOLN2 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Vesicle Scission (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
TGOLN2 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43493 TGOLN2
Gene Names
TGOLN2, TGN46, TGN51
Chain
signal peptide:1-21, chain:22-437
Reference Genes
BioGPS Gene:10618 TGOLN2
COSMIC (genes):TGOLN2 TGOLN2
CTD Gene:10618 TGOLN2
dbSNP Gene:10618 TGOLN2
ENSEMBL:ENSG00000152291 TGOLN2
HGNC:15450 TGOLN2
KEGG Gene (Homo sapiens):10618 TGOLN2
Monarch:10618 TGOLN2
NCBI Gene:10618 TGOLN2
OMIM:603062 TGOLN2
UCSC:O43493 TGOLN2
Reference Transcript
RefSeq:NM_001206840.1 TGOLN2
RefSeq:NM_001206841.1 TGOLN2
RefSeq:NM_006464.3 TGOLN2
RefSeq:NM_001206844.1 TGOLN2
Other Identifiers
0002260162
10618
11489
11716901_s_at
11716902_a_at
11716903_a_at
11716904_s_at
11755687_x_at
12609
12723
1566473_3p_a_at
1566473_a_at
16899619
203833_s_at
203834_s_at
212040_3p_at
212040_at
212043_at
2491521
2562200
2562201
2562202
2562203
2562204
2562205
2562209
2562210
2562211
2562212
2562213
2562214
2562215
2562216
2562217
2562218
2562220
2562221
2562222
2562224
2562226
2562228
2562230
31827_s_at
31828_r_at
31829_r_at
38993_r_at
8053388
A_23_P209933
A_24_P413988
AAB96906
AAB96907
AAB96908
AAC39539
AAC39541
AAC39542
AAH08461
AAH28219
AAY24095
AC093162
AF027515
AF027516
AF029313
AF029314
AF029315
AF029316
AK126465
AK222829
AK223063
AK312479
BAC86559
BAD96549
BAD96783
BAG35383
BC008461
BC028219
BX640868
CAA64002
CAB011489
CAE45926
CCDS46351
CCDS56126
CCDS56127
CH471053
EAW99535
EAW99536
EAW99539
ENSG00000152291
ENSP00000282120
ENSP00000366603
ENSP00000381312
ENSP00000386443
ENSP00000391190
ENST00000282120
ENST00000282120.6
ENST00000377386
ENST00000377386.7
ENST00000398263
ENST00000398263.6
ENST00000409232
ENST00000409232.7
ENST00000444342
ENST00000444342.2
EntrezGene:10618
EntrezGene:TGOLN2
g5454115_3p_a_at
GE81643
GE86506
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005768
GO:0005783
GO:0005788
GO:0005794
GO:0005802
GO:0005886
GO:0006464
GO:0008150
GO:0016020
GO:0016021
GO:0030133
GO:0030140
GO:0030665
GO:0031410
GO:0043226
GO:0043687
GO:0044267
GO:0061024
HGNC:15450
HPA012609
HPA012723
Hs.110771.0.S1_3p_x_at
Hs.110771.0.S2_3p_at
Hs.14894.0.S1_3p_a_at
Hs.14894.0.S1_3p_s_at
ILMN_1651735
MIM:603062
NM_001206840
NM_001206841
NM_001206844
NM_001368096
NM_006464
NP_001193769
NP_001193770
NP_001193773
NP_001355025
NP_006455
PF17818
PH_hs_0001402
PH_hs_0040170
TC02002035.hg
TGOLN2
TGOLN2-201
TGOLN2-202
TGOLN2-203
TGOLN2-205
TGOLN2-206
U62390
UPI0000072C61
UPI0000208801
UPI000020880A
UPI0000EE2512
UPI0004E4CA4A
X94333
X94333_at
Participant Of
hasCandidate
Golgi-associated Vesicle Destined Cargo [Golgi membrane]
Other forms of this molecule
TGOLN2 [endoplasmic reticulum lumen]
p-TGOLN2 [endoplasmic reticulum lumen]
TGOLN2 [transport vesicle]
TGOLN2 [trans-Golgi network membrane]
TGOLN2 [cytoplasmic vesicle membrane]
TGOLN2 [plasma membrane]
TGOLN2 [clathrin-coated endocytic vesicle membrane]
Inferred To
Tgoln1 [Golgi membrane] (Mus musculus)
TGOLN2 [Golgi membrane] (Bos taurus)
TGOLN2 [Golgi membrane] (Canis familiaris)
TGOLN2 [Golgi membrane] (Sus scrofa)
Ttgn1 [Golgi membrane] (Rattus norvegicus)
si:ch1073-392o20.2 [Golgi membrane] (Danio rerio)
Cross References
RefSeq
NP_006455.2
,
NP_001193773.1
,
NP_001193770.1
,
NP_001193769.1
OpenTargets
ENSG00000152291
GeneCards
O43493
HPA
ENSG00000152291-TGOLN2
Ensembl
ENST00000409232
,
ENSP00000366603
,
ENSP00000381312
,
ENST00000377386
,
ENSP00000386443
,
ENST00000398263
,
ENSP00000391190
,
ENST00000444342
,
ENSG00000152291
PRO
O43493
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H3P7 ACBD3
1
ACBD3 [Golgi membrane]
(R-HSA-8874981)
0.577
5
UniProt:P27986 PIK3R1
15
PIK3R1 K379E [plasma membrane]
(R-HSA-8944148)
PIK3R1 G376R [plasma membrane]
(R-HSA-2399717)
PIK3R1 Y463_L466del [plasma membrane]
(R-HSA-2399546)
PIK3R1 H450_E451del [plasma membrane]
(R-HSA-2399545)
PIK3R1 R574_T576del [plasma membrane]
(R-HSA-2399544)
PIK3R1 D560Y [plasma membrane]
(R-HSA-2399421)
PIK3R1 N564D [plasma membrane]
(R-HSA-2399427)
PIK3R1 K459del [plasma membrane]
(R-HSA-2399554)
PIK3R1 N564K [plasma membrane]
(R-HSA-2399431)
PIK3R1 D560H [plasma membrane]
(R-HSA-2399432)
PIK3R1 R574I [plasma membrane]
(R-HSA-2399536)
PIK3R1 R574T [plasma membrane]
(R-HSA-2399540)
K63polyUb-PIK3R1 [cytosol]
(R-HSA-3080572)
PIK3R1 [plasma membrane]
(R-HSA-198365)
PIK3R1 [cytosol]
(R-HSA-74789)
0.564
2
UniProt:Q9NZ52 GGA3
3
GGA3 [early endosome membrane]
(R-HSA-8854137)
GGA3 [endosome membrane]
(R-HSA-5692936)
GGA3 [recycling endosome membrane]
(R-HSA-8875655)
0.491
3
UniProt:Q04721 NOTCH2
18
NOTCH2(1666-1696) [plasma membrane]
(R-HSA-157628)
NOTCH2(1582-1665) [extracellular region]
(R-HSA-157652)
NEXT2 [plasma membrane]
(R-HSA-157225)
NICD2 [cytosol]
(R-HSA-157642)
NICD2 [nucleoplasm]
(R-HSA-157942)
Glc,GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]
(R-HSA-1911428)
Glc,Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]
(R-HSA-1911417)
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]
(R-HSA-1911505)
FRINGE-modified NOTCH2 Extracellular Fragment (NECD2) [plasma membrane]
(R-HSA-1911518)
FRINGE-modified NOTCH2 extracellular fragment (NECD2) [Golgi membrane]
(R-HSA-1911520)
Pre-NOTCH2 [endoplasmic reticulum membrane]
(R-HSA-157025)
18xFucT-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane]
(R-HSA-1467363)
18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane]
(R-HSA-1467379)
18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [Golgi membrane]
(R-HSA-1472874)
NOTCH2(1582-2471) [plasma membrane]
(R-HSA-157228)
18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [extracellular region]
(R-HSA-1983678)
NOTCH2(1582-2471) [Golgi membrane]
(R-HSA-157017)
18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [Golgi membrane]
(R-HSA-1983676)
0.462
2
UniProt:Q14677 CLINT1
1
CLINT1 [cytosol]
(R-HSA-429811)
0.462
4
UniProt:P35613 BSG
2
BSG [Golgi membrane]
(R-HSA-204478)
BSG [plasma membrane]
(R-HSA-197673)
0.462
2
UniProt:Q9NZC7 WWOX
1
WWOX [cytosol]
(R-HSA-1253335)
0.462
2
UniProt:Q14739 LBR
2
LBR [nuclear envelope]
(R-HSA-194637)
p-S71,S86-LBR [nuclear envelope]
(R-HSA-9624811)
0.462
2
UniProt:Q07065 CKAP4
7
PALM-C100-CKAP4 [plasma membrane]
(R-HSA-5686280)
PALM-C100-CKAP4 [lamellar body]
(R-HSA-5686285)
CKAP4 [azurophil granule membrane]
(R-HSA-6799559)
CKAP4 [plasma membrane]
(R-HSA-5686306)
CKAP4 [specific granule membrane]
(R-HSA-6799552)
p-CKAP4 [endoplasmic reticulum lumen]
(R-HSA-8956926)
CKAP4 [endoplasmic reticulum lumen]
(R-HSA-8956737)
0.462
2
UniProt:Q9H2J7 SLC6A15
1
SLC6A15 [plasma membrane]
(R-HSA-352060)
0.462
4
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