CD36 (FAT) translocates palmitate from the extracellular region to the cytosol

Stable Identifier
R-HSA-434381
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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CD36 (FAT) translocates palmitate from the extracellular region to the cytosol
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CD36 (FAT) located in the plasma membrane of pancreatic beta cells transports fatty acids such as palmitate into the cell (Noushmehr et al. 2005).
Literature References
PubMed ID Title Journal Year
15677505 Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion

Doria, A, Noushmehr, H, Wawrowsky, KA, Farilla, L, Mlynarski, W, D'Amico, E, Abumrad, NA, Hui, H, Perfetti, R

Diabetes 2005
Participants
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Output
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as an event of
Catalyst Activity

long-chain fatty acid transporter activity of 4xPalmC-CD36 [plasma membrane]

Physical Entity
4xPalmC-CD36 [plasma membrane] (Homo sapiens)
Activity
long-chain fatty acid transporter activity (GO:0005324)
Orthologous Events
CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Bos taurus)
CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Caenorhabditis elegans)
CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Canis familiaris)
CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Danio rerio)
CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Dictyostelium discoideum)
CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Drosophila melanogaster)
CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Gallus gallus)
CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Mus musculus)
CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Rattus norvegicus)
CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Sus scrofa)
CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Xenopus tropicalis)
Cross References
Rhea
Authored
May, B  (2009-08-28)
Reviewed
D'Eustachio, P  (2018-12-22)
Created
May, B  (2009-08-28)
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