CRAC translocates calcium from the extracellular region to the cytosol

Stable Identifier
R-HSA-434798
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Calcium influx via CRAC
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Activation of Calcium-release-activated (CRAC) channels allows influx of calcium. The Orai component of CRAC is responsible for the selectivity of the channel, while the Stim component is responsible for activation.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
store-operated calcium channel activity of CRAC channel [plasma membrane]
Physical Entity
Activity
Inferred From
Cross References
Rhea
Authored
Reviewed
Created