ZnT3 transports zinc into synaptic vesicles

Stable Identifier
R-HSA-437084
Type
Reaction [transition]
Species
Homo sapiens
Compartment
synaptic vesicle membrane
ReviewStatus
5/5
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ZnT3 transports zinc into synaptic vesicles
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The human gene SLC30A3 encodes zinc transporter ZnT3. Through experiments on the mouse homologue Znt3, it is thought this transporter is expressed mainly in brain and testis and mediated the accumulation of zinc into synaptic vesicles (Palmiter et al, 1996).
Literature References
PubMed ID Title Journal Year
8962159 ZnT-3, a putative transporter of zinc into synaptic vesicles

Findley, SD, Cole, TB, Quaife, CJ, Palmiter, RD

Proc Natl Acad Sci U S A 1996
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Catalyst Activity

zinc ion transmembrane transporter activity of SLC30A3-like Protein [synaptic vesicle membrane]

Physical Entity
SLC30A3-like Protein [synaptic vesicle membrane] (Homo sapiens)
Activity
zinc ion transmembrane transporter activity (GO:0005385)
Inferred From
Znt3 transports zinc into synaptic vesicles (Mus musculus)
Cross References
Rhea
Authored
Jassal, B  (2009-09-11)
Reviewed
He, L  (2009-11-12)
Created
Jassal, B  (2009-09-11)
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