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RASGRF1:RASGRF2 heterooligomer [plasma membrane]
Stable Identifier
R-HSA-442734
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Post NMDA receptor activation events (Homo sapiens)
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling (Homo sapiens)
Ras activation upon Ca2+ influx through NMDA receptor (Homo sapiens)
Activation of RasGRF (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
RASGRF1 oligomer [plasma membrane] (Homo sapiens)
RASGRF1:RASGRF2 heterooligomer [plasma membrane] (Homo sapiens)
RASGRF1 oligomer [plasma membrane] (Homo sapiens)
RASGRF1:RASGRF2 heterooligomer [plasma membrane] (Homo sapiens)
NMDA-activated RASGRF1 activates RAS (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
RASGRF1 oligomer [plasma membrane] (Homo sapiens)
RASGRF1:RASGRF2 heterooligomer [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
RASGRF1 oligomer [plasma membrane] (Homo sapiens)
RASGRF1:RASGRF2 heterooligomer [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
10373510
Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf
Qian, X
,
Papageorge, AG
,
Vass, WC
,
Lowy, DR
,
DeClue, JE
,
Anborgh, PH
Mol Cell Biol
1999
Participants
components
x 2
RASGRF1 [plasma membrane]
(Homo sapiens)
x 2
RASGRF2 [plasma membrane]
(Homo sapiens)
Participates
as a member of
RASGRF1 oligomer [plasma membrane] (Homo sapiens)
Inferred To
RASGRF1:RASGRF2 heterooligomer [plasma membrane]
(Bos taurus)
RASGRF1:RASGRF2 heterooligomer [plasma membrane]
(Canis familiaris)
RASGRF1:RASGRF2 heterooligomer [plasma membrane]
(Gallus gallus)
RASGRF1:RASGRF2 heterooligomer [plasma membrane]
(Mus musculus)
RASGRF1:RASGRF2 heterooligomer [plasma membrane]
(Rattus norvegicus)
RASGRF1:RASGRF2 heterooligomer [plasma membrane]
(Sus scrofa)
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