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KCNQ2 [plasma membrane]
Stable Identifier
R-HSA-443613
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Potassium voltage-gated channel subfamily KQT member 2, KCNQ2_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
Interaction between L1 and Ankyrins (Homo sapiens)
Ankyrins link voltage-gated sodium and potassium channels to spectrin and L1 (Homo sapiens)
KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
KCNQ2,3 [plasma membrane] (Homo sapiens)
KCNQ2 [plasma membrane] (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin:KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
KCNQ2,3 [plasma membrane] (Homo sapiens)
KCNQ2 [plasma membrane] (Homo sapiens)
Neuronal System (Homo sapiens)
Potassium Channels (Homo sapiens)
Voltage gated Potassium channels (Homo sapiens)
Activation of voltage gated Potassium channels (Homo sapiens)
Octamer of Voltage gated K+ channels [plasma membrane] (Homo sapiens)
Voltage gated potassium channel subunits Kv1-12 [plasma membrane] (Homo sapiens)
Kv7 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)
KCNQ2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43526 KCNQ2
Gene Names
KCNQ2
Chain
chain:1-872
Reference Genes
BioGPS Gene:3785 KCNQ2
COSMIC (genes):KCNQ2 KCNQ2
CTD Gene:3785 KCNQ2
dbSNP Gene:3785 KCNQ2
ENSEMBL:ENSG00000075043 KCNQ2
HGNC:6296 KCNQ2
Monarch:3785 KCNQ2
NCBI Gene:3785 KCNQ2
OMIM:602235 KCNQ2
UCSC:O43526 KCNQ2
Reference Transcript
RefSeq:NM_004518.5 KCNQ2
RefSeq:NM_172106.2 KCNQ2
RefSeq:NM_172107.3 KCNQ2
RefSeq:NM_172108.4 KCNQ2
RefSeq:NM_172109.2 KCNQ2
Other Identifiers
11730086_a_at
11737695_a_at
11740180_x_at
11742065_a_at
11751111_a_at
11760640_at
11762096_at
16921224
16921226
205737_PM_at
205737_at
210508_PM_s_at
210508_s_at
211486_PM_s_at
211486_s_at
3785
3913819
3913820
3913822
3913823
3913824
3913825
3913826
3913827
3913828
3913829
3913830
3913831
3913832
3913833
3913834
3913835
3913836
3913837
3913838
3913839
3913840
3913841
3913842
3913843
3913847
3913850
3913851
3913852
3913853
3913854
3913855
3913856
3913857
3913858
3913859
3913860
3913861
3913862
3913864
3913866
3913867
3913868
3913869
3913870
3913871
3913875
3913876
3913877
3913878
3913879
3913885
3913887
3913888
3913889
3913890
3913891
41589_at
8067626
84813_at
A_21_P0010073
A_23_P210400
A_23_P351204
A_23_P422778
A_24_P718503
A_33_P3326807
A_33_P3326812
A_33_P3360753
A_33_P3360758
A_33_P3395823
D82346_at
GE60321
GO:0001508
GO:0005215
GO:0005216
GO:0005249
GO:0005267
GO:0005515
GO:0005516
GO:0005886
GO:0006811
GO:0006813
GO:0007268
GO:0007399
GO:0008076
GO:0008092
GO:0016020
GO:0022843
GO:0023052
GO:0030506
GO:0033268
GO:0034702
GO:0043194
GO:0045202
GO:0048856
GO:0055085
GO:0071805
HMNXSV003009262
HMNXSV003016499
HMNXSV003020408
HMNXSV003024529
HMNXSV003030775
HMNXSV003031342
ILMN_1666776
ILMN_1703500
ILMN_1788663
ILMN_2300894
PH_hs_0026565
PH_hs_0028724
TC20001029.hg
TC20001030.hg
TC20001031.hg
TC20001713.hg
TC20001714.hg
g1841341_3p_a_at
g1841341_3p_x_at
g4324686_3p_a_at
g4758627_3p_at
p21481
p26144
Participates
as a member of
Kv7 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)
KCNQ2,3 [plasma membrane] (Homo sapiens)
Inferred To
KCNQ2 [plasma membrane]
(Bos taurus)
KCNQ2 [plasma membrane]
(Gallus gallus)
KCNQ [plasma membrane]
(Drosophila melanogaster)
Cross References
ZINC - World Drugs
KCNQ2_HUMAN
Guide to Pharmacology - Targets
561
OpenTargets
ENSG00000075043
ENSEMBL
ENSP00000353668
,
ENSP00000486706
,
ENSP00000339611
,
ENST00000626839
,
ENST00000344425
,
ENSP00000352035
,
ENSP00000345523
,
ENST00000360480
,
ENST00000344462
,
ENST00000359125
ZINC - FDA approved
KCNQ2_HUMAN
ZINC - Substances
KCNQ2_HUMAN
ZINC target
O43526
PRO
O43526
PDB
8IJK
,
8J00
,
8IZY
,
8J01
,
7CR0
,
8W4U
,
5J03
,
6FEG
,
7CR7
,
7CR1
,
8J04
,
6FEH
,
8J02
,
7CR3
,
7CR4
,
7CR2
,
8X43
,
8J05
,
8J03
HPA
ENSG00000075043-KCNQ2
Pharos - Targets
O43526
Orphanet
KCNQ2
ZINC - Predictions - Purchasable
KCNQ2_HUMAN
HMDB Protein
HMDBP10839
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