Phosphorylation by MAPK/ERK

Stable Identifier
R-HSA-444253
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Activated MAPK/ERK activates RSK in its C terminal kinase domain by sequentially phosphorylating T573, S363 and 380.

Literature References
PubMed ID Title Journal Year
12832467 Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity

Roux, PP, Richards, SA, Blenis, J

Mol Cell Biol 2003
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
kinase activity of p-T185,Y187-MAPK1 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed