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GPR55 [plasma membrane]
Stable Identifier
R-HSA-444504
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Probable G-protein coupled receptor 55, GPR55_HUMAN, CB3
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
CNRs [plasma membrane] (Homo sapiens)
GPR55 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
CNRs [plasma membrane] (Homo sapiens)
GPR55 [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
CNRs [plasma membrane] (Homo sapiens)
GPR55 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
CNRs [plasma membrane] (Homo sapiens)
GPR55 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
CNRs [plasma membrane] (Homo sapiens)
GPR55 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
CNRs [plasma membrane] (Homo sapiens)
GPR55 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
CNRs bind CNR agonists (Homo sapiens)
CNRs [plasma membrane] (Homo sapiens)
GPR55 [plasma membrane] (Homo sapiens)
CNRs:CNR agonists [plasma membrane] (Homo sapiens)
CNRs [plasma membrane] (Homo sapiens)
GPR55 [plasma membrane] (Homo sapiens)
Cannabinoid receptors can bind cannabinoids (Homo sapiens)
CNRs [plasma membrane] (Homo sapiens)
GPR55 [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
CNRs [plasma membrane] (Homo sapiens)
GPR55 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y2T6 GPR55
Gene Names
GPR55
Chain
chain:1-319
Reference Genes
BioGPS Gene:9290 GPR55
COSMIC (genes):GPR55 GPR55
CTD Gene:9290 GPR55
dbSNP Gene:9290 GPR55
ENSEMBL:ENSG00000135898 GPR55
ENSEMBL_homo_sapiens_GENE:ENSG00000135898.10 GPR55
HGNC:4511 GPR55
KEGG Gene (Homo sapiens):9290 GPR55
Monarch:9290 GPR55
NCBI Gene:9290 GPR55
OMIM:604107 GPR55
UCSC:Q9Y2T6 GPR55
Reference Transcript
RefSeq:XM_011512176.2 GPR55
RefSeq:XM_005246952.3 GPR55
RefSeq:NM_005683.3 GPR55
RefSeq:XM_011512175.2 GPR55
Other Identifiers
11731333_a_at
11731334_a_at
16909464
231745_PM_at
231745_at
237559_PM_at
237559_at
2603321
2603322
2603323
2603324
2603325
2603326
2603327
2603328
2603330
2603340
75650_at
80286_at
8059674
9290
GO:0002376
GO:0004930
GO:0004949
GO:0005886
GO:0007165
GO:0007186
GO:0007200
GO:0007202
GO:0016020
GO:0023052
GO:0030154
GO:0035025
GO:0038171
GO:0045453
GO:0045671
GO:0048856
GO:0060089
GO:0070374
HMNXSV003013870
HMNXSV003042266
Hs.114545.0.S1_3p_at
Hs.147211.0.A1_3p_at
ILMN_1723274
PH_hs_0006295
TC02002856.hg
Participates
as a candidate of
CNRs [plasma membrane] (Homo sapiens)
Inferred To
GPR55 [plasma membrane]
(Bos taurus)
GPR55 [plasma membrane]
(Canis familiaris)
GPR55 [plasma membrane]
(Gallus gallus)
GPR55 [plasma membrane]
(Sus scrofa)
Gpr55 [plasma membrane]
(Mus musculus)
Gpr55 [plasma membrane]
(Rattus norvegicus)
gpr35.1 [plasma membrane]
(Danio rerio)
Cross References
RefSeq
XP_005247009.1
,
NP_005674.2
,
XP_011510477.1
,
XP_011510478.1
ZINC - World Drugs
GPR55_HUMAN
Guide to Pharmacology - Targets
109
OpenTargets
ENSG00000135898
ZINC - Substances
GPR55_HUMAN
ZINC target
Q9Y2T6
ZINC - Biogenic
GPR55_HUMAN
PRO
Q9Y2T6
ZINC - Investigational
GPR55_HUMAN
HPA
ENSG00000135898-GPR55
GeneCards
Q9Y2T6
Ensembl
ENST00000392039
,
ENSP00000375894
,
ENSP00000498258
,
ENST00000392040
,
ENSP00000482381
,
ENST00000444078
,
ENST00000650999
,
ENSP00000375893
,
ENSG00000135898
,
ENSP00000410267
,
ENST00000622008
Pharos - Targets
Q9Y2T6
Orphanet
28469
ZINC - Predictions - Purchasable
GPR55_HUMAN
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17931 LGALS3
3
LGALS3 [ficolin-1-rich granule membrane]
(R-HSA-6803307)
LGALS3 [plasma membrane]
(R-HSA-879445)
LGALS3 [secretory granule membrane]
(R-HSA-6803327)
0.527
2
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