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CXCR5 [plasma membrane]
Stable Identifier
R-HSA-444505
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
C-X-C chemokine receptor type 5, CXCR5_HUMAN, BLR1, CD185
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR5:CXCL13 [plasma membrane] (Homo sapiens)
CXCR5 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR5:CXCL13 [plasma membrane] (Homo sapiens)
CXCR5 [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR5:CXCL13 [plasma membrane] (Homo sapiens)
CXCR5 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR5:CXCL13 [plasma membrane] (Homo sapiens)
CXCR5 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR5:CXCL13 [plasma membrane] (Homo sapiens)
CXCR5 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR5:CXCL13 [plasma membrane] (Homo sapiens)
CXCR5 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Chemokine receptors bind chemokines (Homo sapiens)
CXCR5 binds CXCL13 (Homo sapiens)
CXCR5 [plasma membrane] (Homo sapiens)
CXCR5:CXCL13 [plasma membrane] (Homo sapiens)
CXCR5 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P32302 CXCR5
Gene Names
CXCR5, BLR1, MDR15
Chain
chain:1-372
Reference Genes
BioGPS Gene:643 CXCR5
COSMIC (genes):CXCR5 CXCR5
CTD Gene:643 CXCR5
dbSNP Gene:643 CXCR5
ENSEMBL:ENSG00000160683 CXCR5
ENSEMBL_homo_sapiens_GENE:ENSG00000160683.5 CXCR5
HGNC:1060 CXCR5
KEGG Gene (Homo sapiens):643 CXCR5
Monarch:643 CXCR5
NCBI Gene:643 CXCR5
OMIM:601613 CXCR5
UCSC:P32302 CXCR5
Reference Transcript
RefSeq:NM_032966.2 CXCR5
RefSeq:NM_001716.4 CXCR5
Other Identifiers
1003_s_at
1004_at
11726966_a_at
11733116_a_at
16732037
206126_PM_at
206126_at
216734_PM_s_at
216734_s_at
3351676
3351677
3351683
3351684
3351685
3351687
37455_at
643
7944335
ADDON002906.hg
A_23_P203215
A_24_P252945
GE59942
GO:0000910
GO:0002376
GO:0004930
GO:0005515
GO:0005886
GO:0006935
GO:0006955
GO:0007165
GO:0007186
GO:0007204
GO:0009897
GO:0016020
GO:0016493
GO:0016494
GO:0019722
GO:0019957
GO:0023052
GO:0030595
GO:0032467
GO:0042113
GO:0048535
GO:0048856
GO:0048870
GO:0060089
GO:0060326
GO:0070098
HMNXSV003000850
Hs.113916.2.S1_3p_a_at
ILMN_1699669
ILMN_2337928
ILMN_2337931
PH_hs_0006257
TC11001073.hg
X68149_at
g4502414_3p_at
Participates
as an input of
CXCR5 binds CXCL13 (Homo sapiens)
as a component of
CXCR5:CXCL13 [plasma membrane] (Homo sapiens)
Inferred To
Cxcr5 [plasma membrane]
(Mus musculus)
Cxcr5 [plasma membrane]
(Rattus norvegicus)
npr-32 [plasma membrane]
(Caenorhabditis elegans)
cxcr5 [plasma membrane]
(Xenopus tropicalis)
CXCR5 [plasma membrane]
(Bos taurus)
CXCR5 [plasma membrane]
(Canis familiaris)
CXCR5 [plasma membrane]
(Gallus gallus)
CXCR5 [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001707.1
,
NP_116743.1
Guide to Pharmacology - Targets
72
OpenTargets
ENSG00000160683
GeneCards
P32302
HPA
ENSG00000160683-CXCR5
ZINC target
P32302
Ensembl
ENSP00000292174
,
ENST00000292174
,
ENSG00000160683
PRO
P32302
Pharos - Targets
P32302
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04899 GNAI2
1
GNAI2 [plasma membrane]
(R-HSA-55435)
0.718
7
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