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PAK1 dimer [cytosol]
Stable Identifier
R-HSA-445002
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPHB-mediated forward signaling (Homo sapiens)
PAK1 binds RAC1:GTP (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
L1CAM interactions (Homo sapiens)
Signal transduction by L1 (Homo sapiens)
Interaction of PAK1 with Rac1-GTP (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
Semaphorin interactions (Homo sapiens)
Sema3A PAK dependent Axon repulsion (Homo sapiens)
Activation of PAK by Rac1 (Homo sapiens)
PAK1,2,3 dimer [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Regulation of T cell activation by CD28 family (Homo sapiens)
Co-stimulation by CD28 (Homo sapiens)
CD28 dependent Vav1 pathway (Homo sapiens)
Activation of PAKs by RAC1 and CDC42 (Homo sapiens)
PAK1,2,3 dimer [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
Innate Immune System (Homo sapiens)
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
FCERI mediated MAPK activation (Homo sapiens)
Autophosphorylation of PAK (Homo sapiens)
PAK dimer [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Homo sapiens)
PAK dimer [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
Recruitment of PAK to the membrane by binding active RAC1 (Homo sapiens)
PAK dimer [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Homo sapiens)
PAK dimer [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
RAC1 and CDC42 activate PAK1 (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK6/MAPK4 signaling (Homo sapiens)
Activation of PAKs by RAC1 and CDC42 (Homo sapiens)
PAK1,2,3 dimer [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
VEGFR2 mediated vascular permeability (Homo sapiens)
PAK1-3 autophosphorylates (Homo sapiens)
PAK1,2,3 dimer [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
PAK1-3 dimer disassociates (Homo sapiens)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Homo sapiens)
PAK1,2,3 dimer [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RAC1 binds PAK1-3 (Homo sapiens)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Homo sapiens)
PAK1,2,3 dimer [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
PAK1,2,3 dimer [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases activate PAKs (Homo sapiens)
NF2 binds PAK1 (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
PAK1:NF2 [plasma membrane] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RAC1 and CDC42 activate PAK1 (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 binds effectors at the plasma membrane (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
CDC42:GTP:CDC42 effectors [plasma membrane] (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 binds effectors at the plasma membrane (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RAC1:GTP:RAC1 effectors [plasma membrane] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 binds effectors at the plasma membrane (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 binds effectors at the plasma membrane (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RAC3:GTP:RAC3 effectors [plasma membrane] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RHOH GTPase cycle (Homo sapiens)
RHOH binds effectors at the plasma membrane (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RHOH:GTP:RHOH effectors [plasma membrane] (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RHOJ GTPase cycle (Homo sapiens)
RHOJ binds effectors at the plasma membrane (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RHOJ:GTP:RHOJ effectors [plasma membrane] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ binds effectors at the plasma membrane (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RHOU GTPase cycle (Homo sapiens)
RHOU binds effectors at the plasma membrane (Homo sapiens)
RHOU effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RHOU:GTP:RHOU effectors [plasma membrane] (Homo sapiens)
RHOU effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RHOV GTPase cycle (Homo sapiens)
RHOV binds effectors at the plasma membrane (Homo sapiens)
RHOV effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
RHOV:GTP:RHOV effectors [plasma membrane] (Homo sapiens)
RHOV effectors [cytosol] (Homo sapiens)
PAK1 dimer [cytosol] (Homo sapiens)
Participants
components
x 2
PAK1 [cytosol]
(Homo sapiens)
Participates
as a member of
RHOV effectors [cytosol] (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
RHOU effectors [cytosol] (Homo sapiens)
PAK1,2,3 dimer [cytosol] (Homo sapiens)
PAK dimer [cytosol] (Homo sapiens)
as a candidate of
RAC3 effectors [cytosol] (Homo sapiens)
as an input of
PAK1 binds RAC1:GTP (Homo sapiens)
Interaction of PAK1 with Rac1-GTP (Homo sapiens)
NF2 binds PAK1 (Homo sapiens)
RAC1 and CDC42 activate PAK1 (Homo sapiens)
as a component of
PAK1:NF2 [plasma membrane] (Homo sapiens)
Inferred To
PAK1 dimer [cytosol]
(Bos taurus)
PAK1 dimer [cytosol]
(Caenorhabditis elegans)
PAK1 dimer [cytosol]
(Canis familiaris)
PAK1 dimer [cytosol]
(Dictyostelium discoideum)
PAK1 dimer [cytosol]
(Drosophila melanogaster)
PAK1 dimer [cytosol]
(Gallus gallus)
PAK1 dimer [cytosol]
(Mus musculus)
PAK1 dimer [cytosol]
(Rattus norvegicus)
PAK1 dimer [cytosol]
(Saccharomyces cerevisiae)
PAK1 dimer [cytosol]
(Schizosaccharomyces pombe)
PAK1 dimer [cytosol]
(Sus scrofa)
PAK1 dimer [cytosol]
(Xenopus tropicalis)
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