Phosphorylation of Neurofascin

Stable Identifier
R-HSA-445091
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Phosphorylation of Neurofascin
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The highly conserved FIGQY motif in the cytoplasmic domain of neurofascin is phosphorylated by tyrosine kinases in response to external signals. Phosphorylation of the tyrosine in the FIGQY motif inhibits ankyrin binding.
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Output
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as an event of
Catalyst Activity

protein tyrosine kinase activity of unidentified protein tyrosine kinase [cytosol]

Physical Entity
unidentified protein tyrosine kinase [cytosol] (Homo sapiens)
Activity
protein tyrosine kinase activity (GO:0004713)
Inferred From
Phosphorylation of Neurofascin (Rattus norvegicus)
Authored
Garapati, P V  (2008-07-30)
Reviewed
Maness, PF  (2010-02-16)
Created
Garapati, P V  (2009-10-27)
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