Reactome | ACTA2 [cytosol]

ACTA2 [cytosol]

Stable Identifier

R-HSA-445792

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Actin, aortic smooth muscle, ACTA_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P62736 ACTA2

Gene Names

ACTA2, ACTSA, ACTVS, GIG46

Chain

initiator methionine:, chain:2-377, chain:3-377

Reference Genes

BioGPS Gene:59 ACTA2

COSMIC (genes):ACTA2 ACTA2

CTD Gene:59 ACTA2

dbSNP Gene:59 ACTA2

ENSEMBL:ENSG00000107796 ACTA2

ENSEMBL_homo_sapiens_GENE:ENSG00000107796.13 ACTA2

HGNC:130 ACTA2

KEGG Gene (Homo sapiens):59 ACTA2

Monarch:59 ACTA2

NCBI Gene:59 ACTA2

OMIM:102620 ACTA2

UCSC:P62736 ACTA2

Reference Transcript

Other Identifiers

11722352_s_at

16716350

200974_PM_at

200974_at

32755_at

3299506

3299507

3299508

3299513

3299517

3299520

3299521

3299527

3299531

3299532

3299534

3299540

7934906

A_23_P150053

GO:0000166

GO:0001725

GO:0003012

GO:0003013

GO:0003824

GO:0005524

GO:0005576

GO:0005604

GO:0005615

GO:0005737

GO:0005829

GO:0005856

GO:0005929

GO:0006936

GO:0008217

GO:0009615

GO:0010628

GO:0014829

GO:0015629

GO:0016787

GO:0019901

GO:0023052

GO:0030027

GO:0030154

GO:0030175

GO:0030312

GO:0030485

GO:0031012

GO:0031514

GO:0032991

GO:0043226

GO:0044297

GO:0048856

GO:0048870

GO:0061870

GO:0061874

GO:0070062

GO:0070374

GO:0071560

GO:0072051

GO:0072144

GO:0090131

GO:2000491

HMNXSV003033272

ILMN_1671703

TC10001498.hg

X13839_at

g4501882_3p_s_at

Participates

as a member of

Smooth Muscle Actin [cytosol] (Homo sapiens)

as an output of

ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 (Homo sapiens)

Inferred To

Act88F [cytosol] (Drosophila melanogaster)

Homologues of ACTA2 [cytosol] (Drosophila melanogaster)

Arp53D [cytosol] (Drosophila melanogaster)

Act57B [cytosol] (Drosophila melanogaster)

Act87E [cytosol] (Drosophila melanogaster)

Acta2 [cytosol] (Mus musculus)

Acta2 [cytosol] (Rattus norvegicus)

ACTA2 [cytosol] (Bos taurus)

ACTA2 [cytosol] (Canis familiaris)

ACTA2 [cytosol] (Gallus gallus)

ACTA2 [cytosol] (Sus scrofa)

Act79B [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_001135417.1, NP_001307784.1, NP_001604.1

OpenTargets

ENSG00000107796

GeneCards

P62736

HPA

ENSG00000107796-ACTA2

Ensembl

ENST00000224784, ENSP00000224784, ENSG00000107796

PRO

P62736

Pharos - Targets

P62736

Orphanet

16835