Reactome | GIT2 [cytosol]

GIT2 [cytosol]

Stable Identifier

R-HSA-446034

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

ARF GTPase-activating protein GIT2, GIT2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q14161 GIT2

Gene Names

GIT2, KIAA0148

Chain

chain:1-759

Reference Genes

BioGPS Gene:9815 GIT2

COSMIC (genes):GIT2 GIT2

CTD Gene:9815 GIT2

dbSNP Gene:9815 GIT2

ENSEMBL:ENSG00000139436 GIT2

ENSEMBL_homo_sapiens_GENE:ENSG00000139436.22 GIT2

HGNC:4273 GIT2

KEGG Gene (Homo sapiens):9815 GIT2

Monarch:9815 GIT2

NCBI Gene:9815 GIT2

OMIM:608564 GIT2

UCSC:Q14161 GIT2

Reference Transcript

Other Identifiers

11721292_a_at

11721293_x_at

11721294_a_at

11722765_a_at

11726234_a_at

11746868_a_at

16769983

204982_PM_at

204982_at

209876_PM_at

209876_at

225558_PM_at

225558_at

3471003

3471004

3471006

3471007

3471008

3471009

3471011

3471013

3471015

3471019

3471020

3471021

3471022

3471023

3471027

3471028

3471030

3471033

3471034

3471037

3471039

3471042

3471048

3471051

3471052

3471053

3471054

3471055

3471062

3471063

3471064

3471065

36741_at

48613_at

52136_at

59576_at

7966268

9815

A_23_P204436

A_23_P335848

D63482_at

GE57276

GO:0003824

GO:0005096

GO:0005515

GO:0005634

GO:0005654

GO:0005925

GO:0007420

GO:0008277

GO:0016192

GO:0016301

GO:0016310

GO:0016740

GO:0023052

GO:0031267

GO:0032012

GO:0036465

GO:0043226

GO:0045202

GO:0046872

GO:0048856

GO:0098772

GO:0098793

GO:0110165

HMNXSV003002126

HMNXSV003014175

HMNXSV003049461

Hs.314029.0.A1_3p_at

ILMN_1760922

ILMN_2355776

PH_hs_0025084

TC12001959.hg

g4691727_3p_at

g4691727_3p_x_at

g7661943_3p_at

Participates

as a candidate of

Inferred To

git-1 [cytosol] (Caenorhabditis elegans)

GIT2 [cytosol] (Bos taurus)

GIT2 [cytosol] (Canis familiaris)

GIT2 [cytosol] (Gallus gallus)

GIT2 [cytosol] (Sus scrofa)

Git [cytosol] (Drosophila melanogaster)

Git2 [cytosol] (Mus musculus)

Git2 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_001317082.1, XP_006719770.1, XP_006719772.1, NP_001128686.1, NP_055591.2, NP_476510.1, NP_001128685.1, NP_476511.1

OpenTargets

ENSG00000139436

HPA

ENSG00000139436-GIT2

GeneCards

Q14161

Ensembl

ENST00000355312, ENST00000361006, ENSP00000450348, ENST00000457474, ENSP00000391813, ENST00000547815, ENSP00000447465, ENSG00000139436, ENSP00000354282, ENST00000553118, ENSP00000347464

PRO

Q14161

Pharos - Targets

Q14161

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49023 PXN	4	p-Y-PXN [plasma membrane] (R-HSA-9031680) PXN [plasma membrane] (R-HSA-180493) PXN [cytosol] (R-HSA-210014) p-Y31,Y118-PXN [cytosol] (R-HSA-5218693)	0.688	4
UniProt:Q9Y6K9 IKBKG	12	IKBKG D406V [cytosol] (R-HSA-5262943) IKBKG L153R [cytosol] (R-HSA-5262879) IKBKG E391* [cytosol] (R-HSA-5262924) IKBKG C417R [cytosol] (R-HSA-5262858) IKBKG R173G [cytosol] (R-HSA-5262966) IKBKG R175P [cytosol] (R-HSA-5262916) IKBKG 420Wext447 [cytosol] (R-HSA-5262978) monoSUMO1-K277,K309-IKBKG [nucleoplasm] (R-HSA-4755449) IKBKG [nucleoplasm] (R-HSA-4755413) K63polyUb-IKBKG [cytosol] (R-HSA-202530) Ub-285-IKBKG [cytosol] (R-HSA-741397) IKBKG [cytosol] (R-HSA-168108)	0.618	6
UniProt:Q13153 PAK1	5	PAK1 [plasma membrane] (R-HSA-3928409) p-S144,T423-PAK1 [plasma membrane] (R-HSA-3928472) Active PAK1 [cytosol] (R-HSA-8964622) PAK1 [cytosol] (R-HSA-162629) p-S144,T423-PAK1 [cytosol] (R-HSA-399819)	0.564	3
UniProt:Q13177 PAK2	11	p-S141,T402-PAK2 [plasma membrane] (R-HSA-5096524) PAK2(1-524) [plasma membrane] (R-HSA-164946) p-Y130,S141,T402-PAK2 [cytosol] (R-HSA-5218705) K48polyUb-p-T402-PAK-2p43 [cytosol] (R-HSA-3095873) p-T402-PAK2(213-524) [nucleoplasm] (R-HSA-211709) p-T402-PAK2(213-524) [cytosol] (R-HSA-211654) p-5S-PAK2(2-212) [cytosol] (R-HSA-211588) p-S141,T402-PAK2 [cytosol] (R-HSA-399824) PAK2 [cytosol] (R-HSA-211604) p-5S-PAK2 [cytosol] (R-HSA-211609) PAK2(213-524) [cytosol] (R-HSA-211653)	0.564	2
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.508	2
UniProt:Q9ES28	1	Arhgef7 [cytosol] (R-MMU-430346)	0.499	2

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