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HNF4A [nucleoplasm]
Stable Identifier
R-HSA-446162
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Hepatocyte nuclear factor 4-alpha, HNF4A_HUMAN
Icon
Locations in the PathwayBrowser for interactor UniProt:Q99967 CITED2
Expand all
Developmental Biology (Homo sapiens)
Kidney development (Homo sapiens)
Nephron development (Homo sapiens)
Expression of HNF4A during nephron development (Homo sapiens)
HNF4A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P41235 HNF4A
Gene Names
HNF4A, HNF4, NR2A1, TCF14
Chain
chain:1-474
Reference Genes
COSMIC (genes):HNF4A HNF4A
dbSNP Gene:3172 HNF4A
ENSEMBL:ENSG00000101076 HNF4A
Participates
as a member of
NR [nucleoplasm] (Homo sapiens)
as an output of
Expression of HNF4A during nephron development (Homo sapiens)
Inferred To
nhr-114 [nucleoplasm]
(Caenorhabditis elegans)
nhr-69 [nucleoplasm]
(Caenorhabditis elegans)
Hnf4a [nucleoplasm]
(Mus musculus)
Hnf4a [nucleoplasm]
(Rattus norvegicus)
nhr-47 [nucleoplasm]
(Caenorhabditis elegans)
nhr-68 [nucleoplasm]
(Caenorhabditis elegans)
nhr-64 [nucleoplasm]
(Caenorhabditis elegans)
nhr-40 [nucleoplasm]
(Caenorhabditis elegans)
nhr-49 [nucleoplasm]
(Caenorhabditis elegans)
nhr-14 [nucleoplasm]
(Caenorhabditis elegans)
nhr-35 [nucleoplasm]
(Caenorhabditis elegans)
Hnf4 [nucleoplasm]
(Drosophila melanogaster)
nhr-76 [nucleoplasm]
(Caenorhabditis elegans)
hnf4a [nucleoplasm]
(Xenopus tropicalis)
nhr-118 [nucleoplasm]
(Caenorhabditis elegans)
nhr-17 [nucleoplasm]
(Caenorhabditis elegans)
nhr-1 [nucleoplasm]
(Caenorhabditis elegans)
Homologues of HNF4A [nucleoplasm]
(Caenorhabditis elegans)
nhr-100 [nucleoplasm]
(Caenorhabditis elegans)
HNF4A [nucleoplasm]
(Bos taurus)
HNF4A [nucleoplasm]
(Canis familiaris)
HNF4A [nucleoplasm]
(Gallus gallus)
HNF4A [nucleoplasm]
(Sus scrofa)
nhr-10 [nucleoplasm]
(Caenorhabditis elegans)
nhr-101 [nucleoplasm]
(Caenorhabditis elegans)
Interactors (17)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UBK2 PPARGC1A
4
PPARGC1A [nucleoplasm]
(R-HSA-442481)
p-T178,S539-PPARGC1A [nucleoplasm]
(R-HSA-1592204)
p-T263,S266,T299-PPARGC1A [nucleoplasm]
(R-HSA-1592224)
monoSUMO1-K184-PPARGC1A [nucleoplasm]
(R-HSA-3903023)
0.655
4
UniProt:P04637 TP53
20
Unfolded TP53 [cytosol]
(R-HSA-6813797)
TP53 [cytosol]
(R-HSA-8869337)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
polySUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
TP53 F341C [nucleoplasm]
(R-HSA-9726318)
TP53 G334V [nucleoplasm]
(R-HSA-9726126)
TP53 L330H [nucleoplasm]
(R-HSA-9726124)
TP53 A347T [nucleoplasm]
(R-HSA-9726339)
TP53 R337C [nucleoplasm]
(R-HSA-9726118)
TP53 L344P [nucleoplasm]
(R-HSA-9726075)
TP53 L344R [nucleoplasm]
(R-HSA-9726073)
TP53 R337H [nucleoplasm]
(R-HSA-9726169)
TP53 R337P [nucleoplasm]
(R-HSA-9726168)
TP53 L330P [nucleoplasm]
(R-HSA-9726136)
TP53 L348S [nucleoplasm]
(R-HSA-9726366)
TP53 R337L [nucleoplasm]
(R-HSA-9726163)
TP53 K351E [nucleoplasm]
(R-HSA-9726258)
TP53 F338I [nucleoplasm]
(R-HSA-9726358)
TP53 R342P [nucleoplasm]
(R-HSA-9726101)
TP53 L330R [nucleoplasm]
(R-HSA-9726133)
0.604
3
UniProt:Q92878 RAD50
1
RAD50 [nucleoplasm]
(R-HSA-75160)
0.604
3
UniProt:Q92786 PROX1
0.581
3
IntAct:EBI-10051518 CP2C9
0.576
5
IntAct:EBI-10055672 CP2C8
0.576
3
IntAct:EBI-9980932 UD19
0.576
4
IntAct:EBI-10051521 CP2C9
0.576
5
IntAct:EBI-10050232 ST2A1
0.576
4
IntAct:EBI-10050241 ST2A1
0.576
4
UniProt:Q99967 CITED2
1
CITED2 [nucleoplasm]
(R-HSA-6804489)
0.543
3
IntAct:EBI-10050213 HNF4A-RE
0.524
2
IntAct:EBI-10039564 CO3
0.499
2
IntAct:EBI-10039585 CO3
0.499
2
IntAct:EBI-10034984 GUC2C
0.499
2
IntAct:EBI-9992455 HYEP
0.499
2
IntAct:EBI-9973444 CP2A6
0.499
2
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