Reactome | ESRRG [nucleoplasm]

ESRRG [nucleoplasm]

Stable Identifier

R-HSA-446166

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Estrogen-related receptor gamma, ERR3_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P62508 ESRRG

Gene Names

ESRRG, ERR3, ERRG2, KIAA0832, NR3B3

Chain

chain:1-458

Reference Genes

BioGPS Gene:2104 ESRRG

COSMIC (genes):ESRRG ESRRG

CTD Gene:2104 ESRRG

dbSNP Gene:2104 ESRRG

ENSEMBL:ENSG00000196482 ESRRG

HGNC:3474 ESRRG

KEGG:hsa:2104 ESRRG

Monarch:2104 ESRRG

NCBI Gene:2104 ESRRG

OMIM:602969 ESRRG

UCSC:P62508 ESRRG

Reference Transcript

Participates

as a member of

NR [nucleoplasm] (Homo sapiens)

Inferred To

Esrrg [nucleoplasm] (Mus musculus)

Esrrg [nucleoplasm] (Rattus norvegicus)

knrl [nucleoplasm] (Drosophila melanogaster)

ERR [nucleoplasm] (Drosophila melanogaster)

ESRRG [nucleoplasm] (Bos taurus)

ESRRG [nucleoplasm] (Canis familiaris)

ESRRG [nucleoplasm] (Gallus gallus)

ESRRG [nucleoplasm] (Sus scrofa)

Homologues of ESRRG [nucleoplasm] (Drosophila melanogaster)

kni [nucleoplasm] (Drosophila melanogaster)

eg [nucleoplasm] (Drosophila melanogaster)

Cross References

Guide to Pharmacology - Targets

624

ENSEMBL

ENSP00000419155, ENSP00000375761, ENST00000487276, ENST00000366940, ENSG00000196482, ENST00000616180, ENSP00000419594, ENSP00000352077, ENSP00000418629, ENSP00000355225, ENST00000463665, ENST00000361395, ENSP00000417374, ENST00000673908, ENST00000391890, ENSP00000386171, ENST00000359162, ENSP00000355907, ENSP00000355904, ENSP00000355905, ENSP00000481528, ENSP00000353108, ENST00000366937, ENST00000366938, ENST00000360012, ENST00000493603, ENSP00000354584, ENST00000493748, ENST00000361525, ENST00000408911, ENSP00000500992

OpenTargets

ENSG00000196482

ZINC - Substances

ERR3_HUMAN

ZINC - Biogenic

ERR3_HUMAN

ZINC target

P62508

PRO

P62508

PDB

2GPU, 8BJN, 1KV6, 8BJG, 6Y58, 6K3N, 2GPO, 6I63, 6I64, 2GPP, 1VJB, 2GP7, 6I67, 2ZAS, 6I61, 2P7G, 2P7A, 6I62, 6I66, 6I65, 8IFO, 6XY5, 6KNR, 2EWP, 2E2R, 1TFC, 6Y1D, 2ZKC, 6XXC, 2ZBS, 5YSO, 2P7Z, 8B4Q, 6Y18, 8BM5, 6A6K, 6Y3W, 2GPV

ZINC - Metabolites

ERR3_HUMAN

HPA

ENSG00000196482-ESRRG

GeneCards

ESRRG

Pharos - Targets

P62508

ZINC - Predictions - Purchasable

ERR3_HUMAN

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBK2 PPARGC1A	4	PPARGC1A [nucleoplasm] (R-HSA-442481) p-T178,S539-PPARGC1A [nucleoplasm] (R-HSA-1592204) p-T263,S266,T299-PPARGC1A [nucleoplasm] (R-HSA-1592224) monoSUMO1-K184-PPARGC1A [nucleoplasm] (R-HSA-3903023)	0.722	4
UniProt:A0MZ66 SHTN1	1	KIAA1598 [cytosol] (R-HSA-443599)	0.556	3
UniProt:Q86YN6 PPARGC1B	1	PPARGC1B [nucleoplasm] (R-HSA-1592213)	0.547	2

Cite Us!