PARVA associates with Paxillin

Stable Identifier
R-HSA-446322
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The focal adhesion protein alpha-parvin, interacts with paxillin, through the C-terminal CH-containing fragment of the alpha-parvin and paxillin LD motif (Wang et al., 2008; Lorenz et al., 2008). This interaction likely contributes to the localization of the PINCH-ILK-parvin complexes to focal adhesions.

Literature References
PubMed ID Title Journal Year
18508764 The structure of alpha-parvin CH2-paxillin LD1 complex reveals a novel modular recognition for focal adhesion assembly

Wang, X, Fukuda, K, Byeon, IJ, Velyvis, A, Wu, C, Gronenborn, A, Qin, J

J Biol Chem 2008
18940607 Structural analysis of the interactions between paxillin LD motifs and alpha-parvin

Lorenz, S, Vakonakis, I, Lowe, ED, Campbell, ID, Noble, ME, Hoellerer, MK

Structure 2008
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Orthologous Events
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