Reactome | VASP [cytosol]

VASP [cytosol]

Stable Identifier

R-HSA-446323

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

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Locations in the PathwayBrowser for interactor UniProt:Q9NYB9

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External Reference Information

External Reference

UniProt:P50552 VASP

Gene Names

VASP

Chain

initiator methionine:, chain:2-380

Reference Genes

BioGPS Gene:7408 VASP

COSMIC (genes):VASP VASP

CTD Gene:7408 VASP

dbSNP Gene:7408 VASP

ENSEMBL:ENSG00000125753 VASP

ENSEMBL_homo_sapiens_GENE:ENSG00000125753.15 VASP

HGNC:12652 VASP

KEGG Gene (Homo sapiens):7408 VASP

Monarch:7408 VASP

NCBI Gene:7408 VASP

OMIM:601703 VASP

UCSC:P50552 VASP

Reference Transcript

RefSeq:NM_003370.3 VASP

Other Identifiers

11744034_a_at

16863307

202205_PM_at

202205_at

3836318

3836319

3836320

3836325

3836326

3836327

3836328

3836330

3836332

3836333

3836334

3836335

3836336

3836337

3836339

3836341

3836344

3836349

3836350

3836351

3836359

39105_at

7408

8029710

A_14_P129018

A_23_P119102

GE60407

GO:0001843

GO:0003779

GO:0005515

GO:0005522

GO:0005576

GO:0005615

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005923

GO:0005925

GO:0007010

GO:0007411

GO:0008092

GO:0008154

GO:0015629

GO:0016020

GO:0017124

GO:0030027

GO:0030036

GO:0030154

GO:0030175

GO:0030838

GO:0031258

GO:0031527

GO:0042995

GO:0043226

GO:0045296

GO:0048856

GO:0051289

GO:0065003

GO:0070062

GO:0070161

GO:0110165

HMNXSV003057504

ILMN_1743646

ILMN_1812001

PH_hs_0033125

TC19000649.hg

X98534_s_at

g4507868_3p_x_at

Participates

as a member of

as a component of

MIGFILIN:VASP [cytosol] (Homo sapiens)

as an input of

Migfilin interacts with VASP (Homo sapiens)

Inferred To

VASP [cytosol] (Canis familiaris)

VASP [cytosol] (Gallus gallus)

VASP [cytosol] (Sus scrofa)

vasp [cytosol] (Danio rerio)

vasp [cytosol] (Dictyostelium discoideum)

vasp [cytosol] (Xenopus tropicalis)

ena [cytosol] (Drosophila melanogaster)

unc-34 [cytosol] (Caenorhabditis elegans)

Vasp [cytosol] (Mus musculus)

Vasp [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_003361.1

OpenTargets

ENSG00000125753

HPA

ENSG00000125753-VASP

GeneCards

P50552

Ensembl

ENST00000245932, ENSP00000245932, ENSG00000125753

PRO

P50552

Pharos - Targets

P50552

HMDB Protein

HMDBP02824

PDB

3CHW, 1USD, 1EGX, 1USE, 2PAV, 2PBD

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9P2A4 ABI3			0.718	9
UniProt:Q15942 ZYX			0.666	4
UniProt:Q9NYB9 ABI2	2	ABI2 [cytosol] (R-HSA-1671647) p-4S-ABI2 [cytosol] (R-HSA-2029003)	0.666	5
UniProt:Q9C026 TRIM9	1	TRIM9 [cytosol] (R-HSA-976054)	0.666	4
UniProt:Q702N8 XIRP1			0.654	5
UniProt:Q9UQB8-4 BAIAP2			0.645	6
UniProt:Q9UIG4 PS1C2			0.601	4
UniProt:Q9RI12 YPKA			0.581	4
UniProt:Q8IZP0-5 ABI1			0.556	3
UniProt:O95684 CEP43	3	FGFR1OP(2-163)-FGFR1(429-822) fusion [cytosol] (R-HSA-1604533) FGFR1OP(2-163)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1838994) FGFR1OP [cytosol] (R-HSA-380309)	0.556	3
UniProt:Q13296 SG2A2			0.556	3
UniProt:Q15418 RPS6KA1	7	RPS6KA1 [nucleoplasm] (R-HSA-199860) p-4S,T359,T573-RPS6KA1 [nucleoplasm] (R-HSA-199829) RPS6KA1 [cytosol] (R-HSA-444256) p-T359,S363,T573-RPS6KA1 [cytosol] (R-HSA-9619957) p-S221,T459,S363,S380,T573,S732-RPS6KA1 [cytosol] (R-HSA-9619871) p-T359,S363,S380.T573,S732-RPS6KA1 [cytosol] (R-HSA-9619993) p-S221,T359,S363,S380,T573,S732-RPS6KA1 [nucleoplasm] (R-HSA-444292)	0.544	4
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P22736 NR4A1	2	p-S351-NR4A1 [nucleoplasm] (R-HSA-199846) NR4A1 [nucleoplasm] (R-HSA-199831)	0.524	2
UniProt:A6NGG8 PCARE			0.508	2
UniProt:Q92636 NSMAF	1	NSMAF [cytosol] (R-HSA-5626992)	0.499	2
UniProt:P79114 MYO10			0.489	2
UniProt:Q96MA1 DMRTB			0.488	2
UniProt:P21673 SAT1	1	SAT1 [cytosol] (R-HSA-351236)	0.488	2
UniProt:O43559 FRS3	3	p-5Y-FRS3 [plasma membrane] (R-HSA-191475) FRS3 [plasma membrane] (R-HSA-191482) p-Y-FRS3 [plasma membrane] (R-HSA-9032427)	0.488	2

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