Association of PARVA with TESK1

Stable Identifier
R-HSA-446372
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Association of PARVA with TESK1
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The association of PARVA with TESK1 appears to suppress cell spreading (Lalonde et al. 2005). TESK1 can phosphorylate cofilin and promote F-actin polymerization and cell spreading (Tsumura et al., 2005 ; Toshima et al., 2001; Leeksma et al., 2002). PARVA associates with testicular protein kinase 1 (TESK1) and inhibits its activity (Lalonde et al. 2005).
Literature References
PubMed ID Title Journal Year
15817463 Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin

Bouverat, BP, Brown, MC, Turner, CE, LaLonde, DP

J Biol Chem 2005
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Orthologous Events
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Association of PARVA with TESK1 (Canis familiaris)
Association of PARVA with TESK1 (Danio rerio)
Association of PARVA with TESK1 (Drosophila melanogaster)
Association of PARVA with TESK1 (Gallus gallus)
Association of PARVA with TESK1 (Mus musculus)
Association of PARVA with TESK1 (Rattus norvegicus)
Association of PARVA with TESK1 (Sus scrofa)
Authored
Matthews, L  (2009-10-12)
Reviewed
Wu, C  (2009-11-12)
Created
Matthews, L  (2009-11-12)
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