Reactome | IL10RB [plasma membrane]

IL10RB [plasma membrane]

Stable Identifier

R-HSA-448423

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Interleukin-10 receptor beta chain, I10R2_HUMAN, IL-22R, CRF2-4

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External Reference Information

External Reference

UniProt:Q08334 IL10RB

Gene Names

IL10RB, CRFB4, D21S58, D21S66

Chain

signal peptide:1-19, chain:20-325

Reference Genes

BioGPS Gene:3588 IL10RB

COSMIC (genes):IL10RB IL10RB

CTD Gene:3588 IL10RB

dbSNP Gene:3588 IL10RB

ENSEMBL:ENSG00000243646 IL10RB

ENSEMBL_homo_sapiens_GENE:ENSG00000243646.11 IL10RB

HGNC:5965 IL10RB

KEGG Gene (Homo sapiens):3588 IL10RB

Monarch:3588 IL10RB

NCBI Gene:3588 IL10RB

OMIM:123889 IL10RB

UCSC:Q08334 IL10RB

Reference Transcript

RefSeq:NM_000628.4 IL10RB

Other Identifiers

11727467_x_at

11753111_x_at

1569_r_at

16922243

209575_3p_at

209575_PM_at

209575_at

33227_at

33228_g_at

3588

3918536

3918537

3918540

3918541

3918544

3918545

3918547

3918556

3918565

3918566

3918567

8068254

A_24_P322741

GE86406

GO:0002376

GO:0004920

GO:0005515

GO:0005886

GO:0006091

GO:0006954

GO:0006955

GO:0007165

GO:0016020

GO:0019221

GO:0023052

GO:0032002

GO:0038023

GO:0038196

GO:0046427

GO:0051607

GO:0060089

GO:0098542

GO:0098586

GO:1901857

HMNXSV003033682

ILMN_1767360

ILMN_2230892

PH_hs_0025095

TC21001059.hg

Z17227_at

g12804902_3p_at

Participates

as a component of

as an input of

IL10RB binds TYK2 (Homo sapiens)

Inferred To

CRFB7 [plasma membrane] (Danio rerio)

crfb9 [plasma membrane] (Danio rerio)

zgc:136623 [plasma membrane] (Danio rerio)

Il10rb [plasma membrane] (Mus musculus)

Il10rb [plasma membrane] (Rattus norvegicus)

CRFB4 [plasma membrane] (Danio rerio)

il10rb [plasma membrane] (Xenopus tropicalis)

IL10RB [plasma membrane] (Bos taurus)

IL10RB [plasma membrane] (Canis familiaris)

IL10RB [plasma membrane] (Gallus gallus)

IL10RB [plasma membrane] (Sus scrofa)

CRFB6 [plasma membrane] (Danio rerio)

crfb14 [plasma membrane] (Danio rerio)

Homologues of IL10RB [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_000619.3

Guide to Pharmacology - Targets

1728

OpenTargets

ENSG00000243646

HPA

ENSG00000243646-IL10RB

GeneCards

Q08334

Ensembl

ENST00000290200, ENSG00000243646, ENSP00000290200

PRO

Q08334

Pharos - Targets

Q08334

Orphanet

19498

PDB

6X93, 5T5W, 3LQM

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P22301 IL10	1	IL10 [extracellular region] (R-HSA-447125)	0.589	2
UniProt:Q9GZX6 IL22	1	IL22 [extracellular region] (R-HSA-448460)	0.589	2

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