Formation of caspase-1 p10/p20 dimer

Stable Identifier
R-HSA-448673
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The p10 and p20 subunits first dimerize, then two dimers associate to give the active tetramer.

Literature References
PubMed ID Title Journal Year
8044845 Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

Walker, NP, Talanian, RV, Brady, KD, Dang, LC, Bump, NJ, Ferenz, CR, Franklin, S, Ghayur, T, Hackett, MC, Hammill, LD

Cell 1994
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created
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