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IL20RB [plasma membrane]
Stable Identifier
R-HSA-448709
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Interleukin-20 receptor beta chain, I20RB_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-20 family signaling (Homo sapiens)
IL19 binds IL20RA:JAK1:IL20RB (Homo sapiens)
IL19:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Homo sapiens)
IL19:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB:STAT3 [plasma membrane] (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB:p-Y705-STAT3 [plasma membrane] (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL19:IL20RA:p‑JAK1:IL20RB binds STAT3 (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB:STAT3 [plasma membrane] (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20 binds IL20RA:JAK1:IL20RB (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20 binds to IL22RA1:JAK1:IL20RB (Homo sapiens)
IL20:IL22RA1:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL22RA1:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3 (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3:STAT3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3:p-STAT3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 binds STAT3 (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3:STAT3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20RA binds IL20RB (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24 binds IL20RA:JAK1:IL20RB (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24 binds to IL22RA1:JAK1:IL20RB (Homo sapiens)
IL22RA1:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL22RA1:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL22RA1:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Homo sapiens)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 [plasma membrane] (Homo sapiens)
IL24:IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1,p-STAT3 [plasma membrane] (Homo sapiens)
IL24:IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Homo sapiens)
IL24:IL22RA1:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL22RA1:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB binds STAT3 (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 [plasma membrane] (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 [plasma membrane] (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB:p-STAT3 [plasma membrane] (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 (Homo sapiens)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 [plasma membrane] (Homo sapiens)
IL24:IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Homo sapiens)
IL24:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 (Homo sapiens)
IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1,p-STAT3 [plasma membrane] (Homo sapiens)
IL24:IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
p-STAT3 dissociates from IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3:p-STAT3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
p-STAT3 dissociates from IL24:IL22RA1:p‑JAK1:IL20RB:p‑STAT3 (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB:p-STAT3 [plasma membrane] (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
p‑Y705-STAT3 dissociates from IL19:IL20RA:p-JAK1:IL20RB (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB:p-Y705-STAT3 [plasma membrane] (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RB [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6UXL0 IL20RB
Gene Names
IL20RB, DIRS1, UNQ557/PRO1114
Chain
signal peptide:1-29, chain:30-311
Reference Genes
BioGPS Gene:53833 IL20RB
COSMIC (genes):IL20RB IL20RB
CTD Gene:53833 IL20RB
dbSNP Gene:53833 IL20RB
ENSEMBL:ENSG00000174564 IL20RB
ENSEMBL_homo_sapiens_GENE:ENSG00000174564.13 IL20RB
HGNC:6004 IL20RB
KEGG Gene (Homo sapiens):53833 IL20RB
Monarch:53833 IL20RB
NCBI Gene:53833 IL20RB
OMIM:605621 IL20RB
UCSC:Q6UXL0 IL20RB
Reference Transcript
RefSeq:NM_144717.3 IL20RB
Other Identifiers
11727589_a_at
11727590_a_at
16946077
228575_PM_at
228575_at
2644203
2644204
2644210
2644211
2644212
2644217
2644221
2644222
2644223
2644226
2644227
46172_at
53833
8082916
A_23_P91850
GE548434
GO:0001808
GO:0002376
GO:0002437
GO:0002765
GO:0004896
GO:0005515
GO:0005886
GO:0006954
GO:0007155
GO:0016020
GO:0019221
GO:0023052
GO:0032689
GO:0032703
GO:0032733
GO:0032753
GO:0042015
GO:0042098
GO:0042130
GO:0043029
GO:0048873
GO:0050863
GO:0060089
HMNXSV003017438
Hs.61232.0.A1_3p_at
ILMN_1765668
PH_hs_0003886
TC03003324.hg
Participates
as a component of
IL20:IL22RA1:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL22RA1:JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB [plasma membrane] (Homo sapiens)
IL20RA:JAK1:IL20RB [plasma membrane] (Homo sapiens)
as an input of
IL20RA binds IL20RB (Homo sapiens)
Inferred To
IL20RB [plasma membrane]
(Bos taurus)
IL20RB [plasma membrane]
(Canis familiaris)
IL20RB [plasma membrane]
(Gallus gallus)
IL20RB [plasma membrane]
(Sus scrofa)
Ghost homologue of IL20RB [plasma membrane]
(Danio rerio)
Il20rb [plasma membrane]
(Mus musculus)
Il20rb [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_653318.2
Guide to Pharmacology - Targets
1730
OpenTargets
ENSG00000174564
GeneCards
Q6UXL0
HPA
ENSG00000174564-IL20RB
Ensembl
ENST00000329582
,
ENSP00000328133
,
ENSG00000174564
PRO
Q6UXL0
Pharos - Targets
Q6UXL0
PDB
4DOH
,
6DF3
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NYY1-PRO_0000015381 IL20
0.602
5
UniProt:Q9UHD0-PRO_0000015379 IL19
0.602
4
UniProt:P21145 MAL
0.556
3
UniProt:Q96HA1 POM121
1
POM121 [nuclear envelope]
(R-HSA-157747)
0.527
2
UniProt:Q9BXS4 TMEM59
1
TMEM59 [plasma membrane]
(R-HSA-9714669)
0.527
3
UniProt:P48645 NMU
1
NMU [extracellular region]
(R-HSA-964817)
0.527
3
UniProt:Q96S97 MYADM
0.527
2
UniProt:O43286 B4GALT5
1
B4GALT5 [Golgi membrane]
(R-HSA-1015832)
0.527
2
UniProt:Q9Y397 ZDHHC9
1
ZDHHC9 [Golgi membrane]
(R-HSA-9647931)
0.527
2
UniProt:Q9UHF4 IL20RA
1
IL20RA [plasma membrane]
(R-HSA-448713)
0.524
4
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