Reactome | IL20RA [plasma membrane]

IL20RA [plasma membrane]

Stable Identifier

R-HSA-448713

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Interleukin-20 receptor alpha chain, I20RA_HUMAN

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Locations in the PathwayBrowser for interactor UniProt:Q6UXL0 IL20RB

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External Reference Information

External Reference

UniProt:Q9UHF4 IL20RA

Gene Names

IL20RA, UNQ681/PRO1315

Chain

signal peptide:1-29, chain:30-553

Reference Genes

BioGPS Gene:53832 IL20RA

COSMIC (genes):IL20RA IL20RA

CTD Gene:53832 IL20RA

dbSNP Gene:53832 IL20RA

ENSEMBL:ENSG00000016402 IL20RA

ENSEMBL_homo_sapiens_GENE:ENSG00000016402.14 IL20RA

HGNC:6003 IL20RA

KEGG Gene (Homo sapiens):53832 IL20RA

Monarch:53832 IL20RA

NCBI Gene:53832 IL20RA

OMIM:605620 IL20RA

UCSC:Q9UHF4 IL20RA

Reference Transcript

Other Identifiers

11728363_s_at

11728364_a_at

17024118

219115_PM_s_at

219115_s_at

222829_PM_s_at

222829_s_at

2976040

2976042

2976043

2976044

2976045

2976046

2976049

2976051

2976054

2976055

2976056

2976057

2976061

2976062

2976071

2976072

2976073

2976074

42969_at

53832

68058_at

8129837

84948_at

A_23_P145514

GE532828

GE58592

GO:0004896

GO:0005515

GO:0005886

GO:0012501

GO:0016020

GO:0019221

GO:0023052

GO:0042015

GO:0045124

GO:0060089

GO:2001244

HMNXSV003011060

Hs.21814.0.S1_3p_a_at

ILMN_1695107

PH_hs_0023504

TC06002150.hg

g7657690_3p_a_at

Participates

as a component of

as an input of

JAK1 binds IL20RA (Homo sapiens)

Inferred To

ifnlr1 [plasma membrane] (Danio rerio)

ifngr2 [plasma membrane] (Danio rerio)

ifnar2.2 [plasma membrane] (Xenopus tropicalis)

crfb12 [plasma membrane] (Danio rerio)

IL20RA [plasma membrane] (Bos taurus)

IL20RA [plasma membrane] (Canis familiaris)

IL20RA [plasma membrane] (Gallus gallus)

IL20RA [plasma membrane] (Sus scrofa)

Homologues of IL20RA [plasma membrane] (Danio rerio)

crfb4 [plasma membrane] (Danio rerio)

il22ra2 [plasma membrane] (Danio rerio)

Il20ra [plasma membrane] (Mus musculus)

Il20ra [plasma membrane] (Rattus norvegicus)

il10ra [plasma membrane] (Danio rerio)

Cross References

RefSeq

XP_011534206.1, NP_001265651.1, NP_001265653.1, NP_055247.3, NP_001265652.1

Guide to Pharmacology - Targets

1729

OpenTargets

ENSG00000016402

GeneCards

Q9UHF4

HPA

ENSG00000016402-IL20RA

Ensembl

ENSP00000356722, ENST00000541547, ENSP00000437843, ENSP00000314976, ENSG00000016402, ENST00000367748, ENST00000316649

PRO

Q9UHF4

Pharos - Targets

Q9UHF4

PDB

4DOH

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NYY1-PRO_0000015381 IL20			0.639	4
UniProt:Q15382 RHEB	2	RHEB [endosome membrane] (R-HSA-5656350) RHEB [lysosomal membrane] (R-HSA-165190)	0.527	2
UniProt:P42338 PIK3CB	1	PIK3CB [cytosol] (R-HSA-74788)	0.527	2
UniProt:B0FP48 UPK3L			0.527	2
UniProt:Q9H0W5 CCDC8	1	CCDC8 [cytosol] (R-HSA-8955915)	0.527	2
UniProt:O95057 DIRA1			0.527	2
UniProt:Q99741 CDC6	4	CDC6 [nucleoplasm] (R-HSA-68542) p-CDC6 [nucleoplasm] (R-HSA-5661317) p-CDC6 [cytosol] (R-HSA-68583) CDC6 [cytosol] (R-HSA-113566)	0.527	2
UniProt:Q00341 HDLBP	1	HDLBP [plasma membrane] (R-HSA-8858026)	0.527	2
UniProt:P84085 ARF5	1	ARF5 [cytosol] (R-HSA-6807737)	0.527	2
UniProt:Q9Y6M5 SLC30A1	1	SLC30A1 [plasma membrane] (R-HSA-435361)	0.527	2
UniProt:Q96EK4 THA11			0.527	2
UniProt:O15155 BET1	3	BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688142) BET1 [transport vesicle] (R-HSA-6808719) BET1 [Golgi membrane] (R-HSA-6807743)	0.527	2
UniProt:O95707 POP4	1	POP4 [nucleoplasm] (R-HSA-5696789)	0.527	2
UniProt:P0CG47 UBB	20	UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-109-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-185-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-181-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070)	0.527	2
UniProt:P42336 PIK3CA	20	PIK3CA H1047L [cytosol] (R-HSA-1500714) PIK3CA H1047R [cytosol] (R-HSA-1500716) PIK3CA M1043I [cytosol] (R-HSA-1500719) PIK3CA M1043T [cytosol] (R-HSA-2395934) PIK3CA M1043V [cytosol] (R-HSA-2395932) PIK3CA H1047Y [cytosol] (R-HSA-1500720) PIK3CA E542K [cytosol] (R-HSA-1500701) PIK3CA Q546K [cytosol] (R-HSA-1500705) PIK3CA E545A [cytosol] (R-HSA-2362355) PIK3CA E545K [cytosol] (R-HSA-1500706) PIK3CA E545Q [cytosol] (R-HSA-2362362) PIK3CA Q546E [cytosol] (R-HSA-2362383) PIK3CA E545V [cytosol] (R-HSA-2362365) PIK3CA E542V [cytosol] (R-HSA-2328074) PIK3CA Q546L [cytosol] (R-HSA-2362375) PIK3CA E545G [cytosol] (R-HSA-1500709) PIK3CA Q546H [cytosol] (R-HSA-2362374) PIK3CA Q546R [cytosol] (R-HSA-2362373) PIK3CA Q546P [cytosol] (R-HSA-1500695) PIK3CA E542Q [cytosol] (R-HSA-2328003)	0.527	2
UniProt:Q15545 TAF7	1	TAF7 [nucleoplasm] (R-HSA-212347)	0.527	2
UniProt:Q9UHQ9 CYB5R1	3	CYB5R1 [plasma membrane] (R-HSA-8848888) CYB5R1 [platelet alpha granule membrane] (R-HSA-8848891) CYB5R1 [endoplasmic reticulum membrane] (R-HSA-6806847)	0.527	2
UniProt:Q15036 SNX17			0.527	2
UniProt:Q8TCT0 CERK	1	CERK [plasma membrane] (R-HSA-1631584)	0.527	2
UniProt:O14523 C2C2L			0.527	2
UniProt:Q6UXL0 IL20RB	1	IL20RB [plasma membrane] (R-HSA-448709)	0.524	4

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