IL10 dimerizes

Stable Identifier
R-HSA-449855
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Interleukin-10 is predominantly a noncovalent homodimer with structural similarities to interferon-gamma.

Literature References
PubMed ID Title Journal Year
9836587 Structural and biological stability of the human interleukin 10 homodimer

Syto, R, Murgolo, NJ, Braswell, EH, Mui, P, Huang, E, Windsor, WT

Biochemistry 1998
8897595 Crystal structure of human interleukin-10 at 1.6 A resolution and a model of a complex with its soluble receptor

Zdanov, A, Schalk-Hihi, C, Wlodawer, A

Protein Sci. 1996
Participants
Participant Of
Orthologous Events
Authored
Reviewed