Reactome: A Curated Pathway Database

Interleukin-3 receptor alpha subunit binds Interleukin-3

Stable Identifier
R-HSA-450074
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The Interleukin-3 receptor alpha subunit (IL3Ra) has a single transmembrane domain, a glycosylated extracellular domain and a short (53 amino acids) cytoplasmic tail, containing no tyrosine kinase domain (Kitamura et al. 1991). It binds interleukin-3 with low affinity, and is not capable of signaling by itself.

Literature References
Participants
Participant Of