Reactome: A Curated Pathway Database

p-T69,T71-ATF2

Stable Identifier
R-HSA-450243
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Cyclic AMP-dependent transcription factor ATF-2 (phosphorylated)
Locations in the PathwayBrowser
External Reference Information
External Reference
UniProt:P15336 ATF2
Gene Names
ATF2, CREB2, CREBP1
Chain
chain:1-505
Reference Genes
CTD Gene:1386 ATF2, dbSNP Gene:1386 ATF2, BioGPS Gene:1386 ATF2, NCBI Gene:1386 ATF2, KEGG Gene (Homo sapiens):1386 ATF2, HGNC:784 ATF2, Monarch:1386 ATF2, COSMIC (genes):ATF2 ATF2, OMIM:123811 ATF2, ENSEMBL:ENSG00000115966 ATF2
Reference Transcript
Other Identifiers
 0002680035  11739868_a_at  11750233_a_at  11750480_a_at  11761942_at
 11763586_s_at  1386  1555146_at  16905322  1994_at
 1BHI  1T2K  205446_s_at  212984_at  22134
 2588067  2588068  2588069  2588070  2588071
 2588072  2588073  2588075  2588080  2588081
 2588082  2588086  2588091  2588093  2588094
 2588095  2588096  2588098  2588099  2588103
 2588104  2588106  2588107  2588112  2588113
 2588114  37575_at  3769  38902_r_at  4H36
 8056909  A_23_P209879  A_24_P128145  A_24_P246467  AAA35951
 AAB64017  AAH26175  AAI07699  AAI30336  AAI30338
 AAK55760  AAX88876  AAY15004  AAY17203  AAY17204
 AAY17207  AAY17210  AAY17213  AAY17215  AC007435
 AC074291  AC096649  AC131958  ATF2  ATF2-201
 ATF2-202  ATF2-203  ATF2-205  ATF2-206  ATF2-207
 ATF2-212  AY029364  BC026175  BC107698  BC130335
 BC130337  CAA33886  CAB003769  CCDS2262  CCDS58737
 CCDS58738  CCDS58739  CH471058  DQ003037  DQ003038
 DQ003041  DQ003044  DQ003047  DQ003049  EAX11111
 EAX11112  EAX11113  ENSG00000115966  ENSP00000264110  ENSP00000340576
 ENSP00000376327  ENSP00000386282  ENSP00000386526  ENSP00000387093  ENSP00000407911
 ENST00000264110  ENST00000345739  ENST00000392544  ENST00000409499  ENST00000409635
 ENST00000409833  ENST00000426833  EntrezGene:1386  g4503032_3p_a_at  GE56268
 GE81083  GO:0000122  GO:0000278  GO:0000977  GO:0000980
 GO:0000988  GO:0001071  GO:0001076  GO:0001077  GO:0001102
 GO:0001158  GO:0001228  GO:0003151  GO:0003674  GO:0003676
 GO:0003677  GO:0003682  GO:0003700  GO:0003705  GO:0003713
 GO:0004402  GO:0005515  GO:0005575  GO:0005622  GO:0005623
 GO:0005634  GO:0005654  GO:0005694  GO:0005737  GO:0005739
 GO:0005741  GO:0006351  GO:0006355  GO:0006357  GO:0006366
 GO:0006464  GO:0006810  GO:0006950  GO:0006970  GO:0006974
 GO:0007005  GO:0007049  GO:0008134  GO:0008140  GO:0008150
 GO:0008219  GO:0008283  GO:0009058  GO:0009414  GO:0016020
 GO:0016573  GO:0016740  GO:0016746  GO:0019899  GO:0019901
 GO:0030154  GO:0031573  GO:0032915  GO:0034641  GO:0035497
 GO:0035861  GO:0043167  GO:0043226  GO:0043525  GO:0043565
 GO:0045444  GO:0045944  GO:0046872  GO:0046982  GO:0048646
 GO:0048856  GO:0050680  GO:0051090  GO:0051091  GO:0051276
 GO:0060612  GO:0061024  GO:0097186  GO:1902110  HGNC:784
 HPA022134  Hs.740955  Hs.80285.0.S1_3p_at  Hs2.198166.2.S1_3p_at  Hs2.198166.2.S1_3p_x_at
 ILMN_1748271  IPR004827  IPR013087  IPR016378  IPR029836
 M31630  MIM:123811  NM_001256090  NM_001256091  NM_001256092
 NM_001256093  NM_001256094  NM_001880  NP_001243019  NP_001243020
 NP_001243021  NP_001243022  NP_001243023  NP_001871  NR_045771
 NR_045773  NR_045774  PF00170  PH_hs_0022193  SM00338
 TC02002545.hg  TC02004705.hg  U16028  uc002ujk.5  uc002ujl.4
 uc002ujm.4  uc002ujq.5  uc002ujy.3  uc010fqu.5  uc061pwr.1
 UPI000006E83E  UPI000007213B  UPI000012622B  UPI000013D4BE  UPI00005D3A3E
 X15875  X15875_at
Participant Of
input
hasComponent
output
This entity regulates
Positive Regulation
Other forms of this molecule
ATF2 [nucleoplasm]
Inferred To
Modified Residues
Name Coordinate Modification PsiMod
O-phospho-L-threonine at 71 71
O-phospho-L-threonine [MOD:00047] A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
O-phospho-L-threonine at 69 69
O-phospho-L-threonine [MOD:00047] A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_001243020.1, NP_001243019.1, NP_001871.2, NP_001243023.1, NP_001243022.1, NP_001243021.1
UCSC human
P15336
GeneCards
P15336
DOCK Blaster
4H36, 1T2K
PRO
P15336
HMDB Protein
HMDBP08112
PDB
4H36, 1BHI, 1T2K
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.866 P05412 JUN_HUMAN 14
0.819 P01100 FOS_HUMAN 9
0.696 P63165 SUMO1_HUMAN 5
0.646 P15408 FOSL2_HUMAN 4
0.592 P17275 JUNB_HUMAN 2
0.576 P21796 VDAC1_HUMAN 3
0.576 P19367 HXK1_HUMAN 4
0.571 Q99986 VRK1_HUMAN 5
0.558 P0C746 HBZ_HTL1A 3
0.556 P45984 MK09_HUMAN 5
0.556 Q9BVG8 KIFC3_HUMAN 3
0.556 Q6FG41 Q6FG41_HUMAN 3
0.556 Q96B26 EXOS8_HUMAN 3
0.532 A4PIW0 A4PIW0_HUMAN 11
0.508 Q8IUH5 ZDH17_HUMAN 3
0.499 Q15532 SSXT_HUMAN 2
0.499 O95644 NFAC1_HUMAN 2
0.488 P53539 FOSB_HUMAN 2
0.488 O75928-2 PIAS2 2
0.488 Q8N9N5-2 BANP 2
0.488 Q6IQ16 SPOPL_HUMAN 2
0.488 F5H3M2 F5H3M2_HUMAN 2
0.462 Q04724 TLE1_HUMAN 10
 
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