p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta

Stable Identifier
R-HSA-450394
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Phosphorylated tristetraproline (TTP) binds 14-3-3, which inhibits the ability of TTP to destabilize RNA. Thus RNAs bound by TTP become stabilized. The binding of 14-3-3 causes TTP to be excluded from stress granules.

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