Reactome | PELI1 [cytosol]

PELI1 [cytosol]

Stable Identifier

R-HSA-450696

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Pellino-1, Protein pellino homolog 1, PELI1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96FA3 PELI1

Gene Names

PELI1, PRISM

Chain

chain:1-418

Reference Genes

BioGPS Gene:57162 PELI1

COSMIC (genes):PELI1 PELI1

CTD Gene:57162 PELI1

dbSNP Gene:57162 PELI1

ENSEMBL:ENSG00000197329 PELI1

ENSEMBL_homo_sapiens_GENE:ENSG00000197329.12 PELI1

HGNC:8827 PELI1

KEGG Gene (Homo sapiens):57162 PELI1

Monarch:57162 PELI1

NCBI Gene:57162 PELI1

OMIM:614797 PELI1

UCSC:Q96FA3 PELI1

Reference Transcript

Other Identifiers

11733060_a_at

11733061_s_at

11744529_a_at

11745912_a_at

16898326

218319_PM_at

218319_at

2556303

2556304

2556305

2556308

2556309

2556311

2556313

2556319

2556327

2556328

2556343

2556344

54982_at

57162

8052654

87415_at

A_23_P120345

A_33_P3316928

GE62487

GO:0000209

GO:0001819

GO:0002376

GO:0003824

GO:0004842

GO:0005515

GO:0005634

GO:0005829

GO:0007155

GO:0008592

GO:0012501

GO:0016567

GO:0016740

GO:0023052

GO:0030163

GO:0030890

GO:0031398

GO:0032496

GO:0034141

GO:0034145

GO:0034450

GO:0036211

GO:0042098

GO:0042110

GO:0042130

GO:0043123

GO:0043161

GO:0043226

GO:0043331

GO:0050868

GO:0050871

GO:0060544

GO:0060546

GO:0061630

GO:0070534

GO:0070936

GO:0098542

GO:0140096

HMNXSV003011022

ILMN_1679268

PH_hs_0000813

TC02001911.hg

g11037062_3p_at

Participates

as a member of

Pellino 1,2,3 [cytosol] (Homo sapiens)

as a component of

as an input of

PELI1 binds activated RIPK1:RIPK3 (Homo sapiens)

Other forms of this molecule

p-PELI1 [cytosol]

Inferred To

PELI1 [cytosol] (Bos taurus)

PELI1 [cytosol] (Canis familiaris)

PELI1 [cytosol] (Gallus gallus)

PELI1 [cytosol] (Rattus norvegicus)

PELI1 [cytosol] (Sus scrofa)

peli-1 [cytosol] (Caenorhabditis elegans)

peli1b [cytosol] (Danio rerio)

Pli [cytosol] (Drosophila melanogaster)

peli1 [cytosol] (Xenopus tropicalis)

Peli1 [cytosol] (Mus musculus)

Cross References

RefSeq

NP_065702.2, XP_011531296.1, XP_016860009.1

OpenTargets

ENSG00000197329

GeneCards

Q96FA3

HPA

ENSG00000197329-PELI1

Ensembl

ENSP00000351789, ENSG00000197329, ENST00000358912

PRO

Q96FA3

Pharos - Targets

Q96FA3

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NWZ3 IRAK4	9	IRAK4 Q293* [cytosol] (R-HSA-5602426) IRAK4 R12C [cytosol] (R-HSA-5602511) IRAK4 E402* [cytosol] (R-HSA-5602517) p-T342,T345,S346-IRAK4 [cytosol] (R-HSA-446649) IRAK4 [endosome membrane] (R-HSA-975167) p-T342,T345,S346-IRAK4 [endosome membrane] (R-HSA-975149) IRAK4 [plasma membrane] (R-HSA-937051) p-T342,T345,S346-IRAK4 [plasma membrane] (R-HSA-936957) IRAK4 [cytosol] (R-HSA-166081)	0.775	6
UniProt:P51617 IRAK1	14	K63polyUb-hp-IRAK1 [endosome membrane] (R-HSA-975112) p-S376,T387-IRAK1 [cytosol] (R-HSA-446687) p-S,T-IRAK1 [cytosol] (R-HSA-3149574) K63polyUb-hp-IRAK1 [cytosol] (R-HSA-451565) p-T209-IRAK1 [endosome membrane] (R-HSA-975189) p-T209,T387-IRAK1 [endosome membrane] (R-HSA-975117) IRAK1 [endosome membrane] (R-HSA-975127) p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (R-HSA-975157) IRAK1 [plasma membrane] (R-HSA-937045) p-T209-IRAK1 [plasma membrane] (R-HSA-937031) p-T209,T387-IRAK1 [plasma membrane] (R-HSA-166279) p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (R-HSA-937011) p-2S,S376,T,T209,T387-IRAK1 [cytosol] (R-HSA-446682) IRAK1 [cytosol] (R-HSA-446639)	0.734	4
UniProt:P80188 LCN2	2	LCN2 [specific granule lumen] (R-HSA-6799614) LCN2 [extracellular region] (R-HSA-5215934)	0.556	3
UniProt:A0A6Q8PF08 A0A6Q8PF08			0.556	3
UniProt:Q9Y3C0 WASC3			0.556	3
UniProt:Q9H426 RIMS4			0.556	3
UniProt:P02545 LMNA	3	LMNA(1-646) [nuclear envelope] (R-HSA-535479) LMNA(1-567)-RAF1(279-648) fusion [cytosol] (R-HSA-6802399) LMNA(1-567)-p-RAF1(279-648) fusion [cytosol] (R-HSA-6802537)	0.556	3
UniProt:Q9H3D4 TP63	1	TP63 [nucleoplasm] (R-HSA-2997585)	0.556	3
UniProt:Q6ZS10 CL17A			0.556	3
UniProt:O14653 GOSR2	4	GOSR2 [endoplasmic reticulum membrane] (R-HSA-5689451) GOSR2 [ER to Golgi transport vesicle membrane] (R-HSA-5689800) GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-535472) GOSR2 [Golgi membrane] (R-HSA-6807755)	0.556	3
UniProt:Q13442 PDAP1	2	PDAP1 [extracellular region] (R-HSA-6806445) PDAP1 [ficolin-1-rich granule lumen] (R-HSA-6800417)	0.556	3
UniProt:Q8N137 CNTRB			0.556	3
UniProt:Q08AM6 VAC14	3	VAC14 [Golgi membrane] (R-HSA-1806235) VAC14 [early endosome membrane] (R-HSA-1806207) VAC14 [late endosome membrane] (R-HSA-1806219)	0.556	3
UniProt:Q15735 INPP5J	1	INPP5J [cytosol] (R-HSA-1604590)	0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:Q15645 PCH2			0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:O15151 MDM4	5	PolyUb-MDM4 [nucleoplasm] (R-HSA-6782502) p-S403-MDM4 [nucleoplasm] (R-HSA-349461) p-S346,S367,S403-MDM4 [nucleoplasm] (R-HSA-349441) PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm] (R-HSA-6804938) MDM4 [nucleoplasm] (R-HSA-349430)	0.527	2

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