Microtubule-independent trafficking of connexons to the plasma membrane

Stable Identifier
R-HSA-451056
Type
Reaction
Species
Homo sapiens
Compartment
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Summation

Connexons may also traffic using a microtubule-independent mechanism. A few studies suggest that rough ER membranes can directly transfer connexons to the plasma membrane (Martin et al. 2001; Bloom and Goldstein 1998). Other cytoskeletal components, such as actin filaments, might be involved in the delivery of connexons to gap junction plaques (Thomas et al. 2001; Gilleron et al. 2006).

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Authored