Activation of Ca-permeable Kainate receptors

Stable Identifier
R-HSA-451311
Type
Reaction
Species
Homo sapiens
Compartment
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Kainate receptors that are assembled with subunits GRIK1-5, are Ca2+ permeable if GRIK1 and GRIK2 are not edited at the Q/R or other sites.
These channels permit Ca2+ upon activation by glutamate or other agonists.

Literature References
PubMed ID Title Journal Year
9625352 Functional AMPA/kainate receptors in human embryonic and foetal central nervous system

Bardoul, M, K├Ânig, N, Levallois, C

J Chem Neuroanat 1998
8782898 Cytotoxic effects of kainate ligands on HEK cell lines expressing recombinant kainate receptors

Giordano, T, Cortes-Burgos, L, Carver, JM, Shu, J, Howe, JR, Mansson, PE, Zhou, LM

Brain Res 1996
Participants
Participates
Catalyst Activity

ligand-gated ion channel activity of Kainate receptor-glutamate complex [plasma membrane]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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