PGYB dimer, b form + 2 AMP <=> PGYB b dimer:AMP complex

Stable Identifier
R-HSA-453356
Type
Reaction
Species
Homo sapiens
Compartment
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Summation

Cytosolic, non-phosphorylated PGYB dimers (b form) can reversibly bind AMP. This reaction is inferred from the AMP-binding properties of human PGYL and closely homologous PGYM proteins from other species (Newgard et al. 1989; Rath et al. 2000).

Literature References
PubMed ID Title Journal Year
2667896 The family of glycogen phosphorylases: structure and function

Newgard, CB, Hwang, PK, Fletterick, RJ

Crit Rev Biochem Mol Biol 1989
10949035 Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core

Rath, VL, Ammirati, M, LeMotte, PK, Fennell, KF, Mansour, MN, Danley, DE, Hynes, TR, Schulte, GK, Wasilko, DJ, Pandit, J

Mol Cell 2000
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