polySUMO2-VDR [nucleoplasm]

Stable Identifier
R-HSA-4546376
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Vitamin D3 receptor, VDR_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
22564762 PIAS4 represses vitamin D receptor-mediated signaling and acts as an E3-SUMO ligase towards vitamin D receptor

Lee, WP, Thompson, PD, Doherty, D, Jena, S

J. Steroid Biochem. Mol. Biol. 2012
External Reference Information
External Reference
Gene Names
VDR, NR1I1
Chain
chain:1-427
Other Identifiers
11728776_s_at
11728777_a_at
11750983_a_at
11758546_x_at
1388_g_at
1410_at
16763764
204253_PM_s_at
204253_s_at
204254_PM_s_at
204254_s_at
204255_PM_s_at
204255_s_at
3452817
3452819
3452820
3452821
3452822
3452824
3452825
3452827
3452831
3452833
3452835
3452848
3452849
57460_at
7421
7962689
A_23_P162589
GE57479
GO:0000122
GO:0000785
GO:0000902
GO:0000978
GO:0000981
GO:0001501
GO:0003676
GO:0003677
GO:0003700
GO:0004879
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006816
GO:0006874
GO:0007595
GO:0008270
GO:0008285
GO:0008289
GO:0009887
GO:0010628
GO:0010839
GO:0010980
GO:0012501
GO:0016071
GO:0022414
GO:0022600
GO:0023052
GO:0030154
GO:0030501
GO:0030522
GO:0035435
GO:0036094
GO:0038183
GO:0038186
GO:0042789
GO:0043226
GO:0043235
GO:0043565
GO:0045618
GO:0045892
GO:0045944
GO:0046697
GO:0046872
GO:0046965
GO:0048856
GO:0050892
GO:0055065
GO:0055085
GO:0060057
GO:0060058
GO:0060089
GO:0060558
GO:0060745
GO:0070561
GO:0070564
GO:0070644
GO:0090575
GO:0140110
GO:1902098
GO:1902121
GO:1903412
HMNXSV003010726
HMNXSV003043975
Hs.2062.0.A2_3p_a_at
Hs.2062.0.A3_3p_a_at
ILMN_1869034
ILMN_2319952
J03258_at
PH_hs_0000277
TC12001439.hg
TC12002858.hg
g4507882_3p_a_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
sumoylated lysine (polySUMO2 [nucleoplasm]) at unknown position
Modification
polySUMO2 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
ZINC - World Drugs
Guide to Pharmacology - Targets
605
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Investigational
ZINC - Metabolites
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (14)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P19793 RXRA  4 0.791 6
 UniProt:Q15648 MED1  1 0.743 4
 UniProt:Q13573 SNW1  1 0.667 5
 UniProt:Q15788 NCOA1  3 0.656 3
 UniProt:Q13501 SQSTM1  7 0.591 4
 UniProt:P28700 Rxra  5 0.576 3
 UniProt:P50222 MEOX2      0.556 3
 UniProt:Q15645 PCH2      0.556 3
 UniProt:Q09472 EP300  5 0.547 3
 UniProt:P04637 TP53  20 0.537 6
 IntAct:EBI-9915211 CO1A1      0.524 2
 UniProt:Q15596 NCOA2  3 0.524 2
 UniProt:P26045 PTPN3  3 0.524 4
 UniProt:Q9JLI4 NCOA6      0.508 2
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