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HIST1H2AA [nucleoplasm]
Stable Identifier
R-HSA-4549203
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Histone H2A type 1-A, H2A1A_HUMAN
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HATs acetylate histones (Homo sapiens)
EP300 acetylates histone H2A, H2B, H3, H4 (Homo sapiens)
Histone H2A, H2B, H3, H4 [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
NuA4 complex acetylates histone H2A, HIST1H4 (Homo sapiens)
Histone H2A, HIST1H4 [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
HDACs deacetylate histones (Homo sapiens)
HDAC10 deacetylates histone (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
HDAC1:2-containing complex deacetylate histones (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
HDAC3 containing complexes deacetylate histone (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
HDAC8 deacetylates histones (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
RMTs methylate histone arginines (Homo sapiens)
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Homo sapiens)
MeR12-histone H2A, Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Homo sapiens)
MeR4-histone H2A, Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
PRMT6 methylates histone H2A arginine-30 (H2AR29) (Homo sapiens)
MeR30-histone H2A, Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Early Events (Homo sapiens)
Activation of Latent HCMV Genome (Homo sapiens)
Latent Transcriptionally Repressed HCMV Genome [nucleoplasm] (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
Latent Transcriptinally Repressed HCMV Genome (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
Latent Transcriptionally Repressed HCMV Genome [nucleoplasm] (Homo sapiens)
Core histone octamer [nucleoplasm] (Homo sapiens)
Histone H2A:H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Metalloprotease DUBs (Homo sapiens)
BRCA1-A complex deubiquitinates K63polyUb-histone H2A (Homo sapiens)
BRCA1-A Complex:Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
MYSM1 deubiquitinates Histone H2A (Homo sapiens)
MYSM1:EP300:KAT2B:Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
UCH proteinases (Homo sapiens)
Histone H2A is dubiquitinated by the PR-DUB complex (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP16,USP21 deubiquitinate Histone H2A (Homo sapiens)
USP16,USP22:Histone H2A [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
USP3,SAGA:Histone H2A,Histone H2B [nucleoplasm] (Homo sapiens)
Histone H2A,Histone H2B [nucleoplasm] (Homo sapiens)
Histone H2A [nucleoplasm] (Homo sapiens)
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
HIST1H2AA [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96QV6 H2AC1
Gene Names
H2AC1, H2AFR, HIST1H2AA
Chain
initiator methionine:, chain:2-131
Reference Genes
BioGPS Gene:221613 H2AC1
CTD Gene:221613 H2AC1
dbSNP Gene:221613 H2AC1
ENSEMBL:ENSG00000164508 HIST1H2AA
ENSEMBL_homo_sapiens_GENE:ENSG00000164508.6 H2AC1
HGNC:18729 H2AC1
KEGG Gene (Homo sapiens):221613 H2AC1
Monarch:221613 H2AC1
NCBI Gene:221613 H2AC1
OMIM:613499 H2AC1
UCSC:Q96QV6 H2AC1
Reference Transcript
RefSeq:NM_170745.3 H2AC1
Other Identifiers
11740813_at
17016296
221613
2946051
2946052
2946053
2946054
2946055
2946057
2946099
8124331
A_23_P355439
GE893547
GO:0000781
GO:0000786
GO:0001674
GO:0003677
GO:0005198
GO:0005576
GO:0005615
GO:0005634
GO:0005694
GO:0006325
GO:0030527
GO:0043226
GO:0043229
GO:0046982
GO:0070062
HMNXSV003009216
ILMN_1694166
PH_hs_0033163
TC06001335.hg
Participates
as a member of
Histone HIST1H2A [nucleoplasm] (Homo sapiens)
Other forms of this molecule
K63polyUb-HIST1H2AA [nucleoplasm]
Ub-HIST1H2AA [nucleoplasm]
Ack-HIST1H2AA [nucleoplasm]
MeR12-HIST1H2AA [nucleoplasm]
Me2aR12-HIST1H2AA [nucleoplasm]
Me2sR4-HIST1H2AA [nucleoplasm]
MeR4-HIST1H2AA [nucleoplasm]
Me2aR4-HIST1H2AA [nucleoplasm]
MeR30-HIST1H2AA [nucleoplasm]
Me2aR30-HIST1H2AA [nucleoplasm]
Ack6-HIST1H2AA [nucleoplasm]
Inferred To
HIST1H2AA [nucleoplasm]
(Gallus gallus)
HIST1H2AA [nucleoplasm]
(Plasmodium falciparum)
HIST1H2AA [nucleoplasm]
(Sus scrofa)
LOC100485548 [nucleoplasm]
(Xenopus tropicalis)
LOC100487632 [nucleoplasm]
(Xenopus tropicalis)
LOC116411633 [nucleoplasm]
(Xenopus tropicalis)
his-35 [nucleoplasm]
(Caenorhabditis elegans)
HTA1 [nucleoplasm]
(Saccharomyces cerevisiae)
HTA2 [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of HIST1H2AA [nucleoplasm]
(Caenorhabditis elegans)
Homologues of HIST1H2AA [nucleoplasm]
(Danio rerio)
Homologues of HIST1H2AA [nucleoplasm]
(Dictyostelium discoideum)
Homologues of HIST1H2AA [nucleoplasm]
(Drosophila melanogaster)
Homologues of HIST1H2AA [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of HIST1H2AA [nucleoplasm]
(Schizosaccharomyces pombe)
Homologues of HIST1H2AA [nucleoplasm]
(Xenopus tropicalis)
H2Av2 [nucleoplasm]
(Dictyostelium discoideum)
His2A:CG33862 [nucleoplasm]
(Drosophila melanogaster)
hta1 [nucleoplasm]
(Schizosaccharomyces pombe)
his-65 [nucleoplasm]
(Caenorhabditis elegans)
hta2 [nucleoplasm]
(Schizosaccharomyces pombe)
h2ac16 [nucleoplasm]
(Xenopus tropicalis)
LOC614881 [nucleoplasm]
(Bos taurus)
LOC116407737 [nucleoplasm]
(Xenopus tropicalis)
LOC100487067 [nucleoplasm]
(Xenopus tropicalis)
h2ax1 [nucleoplasm]
(Danio rerio)
zgc:56685 [nucleoplasm]
(Danio rerio)
H2AX [nucleoplasm]
(Dictyostelium discoideum)
H2Av3 [nucleoplasm]
(Dictyostelium discoideum)
htas-1 [nucleoplasm]
(Caenorhabditis elegans)
H2AC1 [nucleoplasm]
(Canis familiaris)
H2Av1 [nucleoplasm]
(Dictyostelium discoideum)
H2ac1 [nucleoplasm]
(Mus musculus)
LOC101732059 [nucleoplasm]
(Xenopus tropicalis)
His2A:CG33859 [nucleoplasm]
(Drosophila melanogaster)
Cross References
RefSeq
NP_734466.1
OpenTargets
ENSG00000164508
HPA
ENSG00000164508-H2AC1
GeneCards
Q96QV6
Ensembl
ENST00000703603
,
ENST00000297012
,
ENSG00000164508
,
ENSP00000515391
,
ENSP00000297012
PRO
Q96QV6
Pharos - Targets
Q96QV6
HMDB Protein
HMDBP07726
PDB
5GSU
,
5GT0
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