Reactome | AcK-HIST1H2BJ [nucleoplasm]

AcK-HIST1H2BJ [nucleoplasm]

Stable Identifier

R-HSA-4549258

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Histone H2B.r

Locations in the PathwayBrowser

Expand all

Chromatin organization (Homo sapiens)

- Chromatin modifying enzymes (Homo sapiens)
  - HATs acetylate histones (Homo sapiens)
    - ATF2 acetylates histone H2B, H4 (Homo sapiens)
      - AcK-replicative histone H2B, H4 [nucleoplasm] (Homo sapiens)
        
        AcK-histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK-histone HIST1H2B [nucleoplasm] (Homo sapiens)
        
        AcK-HIST1H2BJ [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:P06899 H2BC11

Gene Names

H2BC11, H2BFR, HIST1H2BJ

Chain

initiator methionine:1, chain:2-126

Reference Genes

BioGPS Gene:8970 H2BC11

CTD Gene:8970 H2BC11

dbSNP Gene:8970 H2BC11

ENSEMBL:ENSG00000124635 HIST1H2BJ

HGNC:4761 H2BC11

KEGG Gene (Homo sapiens):8970 H2BC11

Monarch:8970 H2BC11

NCBI Gene:8970 H2BC11

OMIM:615044 H2BC11

UCSC:P06899 H2BC11

Reference Transcript

RefSeq:NM_021058.3 H2BC11

Other Identifiers

0006400546

11741699_at

11741700_s_at

11741701_x_at

153_f_at

17016451

2946699

2946700

2946709

2946710

2946711

2946712

8124484

85177_at

8970

A_24_P359231

A_24_P55148

GE85150

GO:0000786

GO:0001530

GO:0002227

GO:0002376

GO:0003674

GO:0003677

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0005886

GO:0006334

GO:0006464

GO:0006950

GO:0007165

GO:0008150

GO:0008289

GO:0010804

GO:0016567

GO:0019731

GO:0022607

GO:0031640

GO:0032991

GO:0042742

GO:0043226

GO:0046982

GO:0050829

GO:0050830

GO:0051276

GO:0061844

GO:0065003

ILMN_1658702

PH_hs_0035577

TC06001385.hg

TC06001386.hg

X00088_at

Participant Of

hasMember

AcK-histone HIST1H2B [nucleoplasm]

Other forms of this molecule

HIST1H2BJ [extracellular region]

Ub-HIST1H2BJ [nucleoplasm]

AcK21-HIST1H2BJ [nucleoplasm]

AcK6-HIST1H2BJ [nucleoplasm]

AcK16-HIST1H2BJ [nucleoplasm]

AcK13-HIST1H2BJ [nucleoplasm]

Ub-121-HIST1H2BJ [nucleoplasm]

HIST1H2BJ [nucleoplasm]

Inferred To

AcK-HIST1H2BB [nucleoplasm] (Plasmodium falciparum)

His2B [nucleoplasm] (Drosophila melanogaster)

H2BC11 [nucleoplasm] (Bos taurus)

H2BC11 [nucleoplasm] (Sus scrofa)

h2bc14 [nucleoplasm] (Xenopus tropicalis)

Homologues of AcK-HIST1H2BB [nucleoplasm] (Caenorhabditis elegans)

Homologues of AcK-HIST1H2BB [nucleoplasm] (Saccharomyces cerevisiae)

htb1 [nucleoplasm] (Schizosaccharomyces pombe)

his-54 [nucleoplasm] (Caenorhabditis elegans)

H2B-VI [nucleoplasm] (Gallus gallus)

AcK-HIST1H2BJ [nucleoplasm] (Canis familiaris)

his-34 [nucleoplasm] (Caenorhabditis elegans)

H2Bv3 [nucleoplasm] (Dictyostelium discoideum)

hist2h2l [nucleoplasm] (Danio rerio)

H2bc21 [nucleoplasm] (Mus musculus)

HTB1 [nucleoplasm] (Saccharomyces cerevisiae)

Hist2h2be [nucleoplasm] (Rattus norvegicus)

HTB2 [nucleoplasm] (Saccharomyces cerevisiae)

Modified Residues

Name

N6-acetyl-L-lysine at unknown position

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Cross References

RefSeq

NP_066402.2

Target Pathogen

5b354852be737e166372ec68

OpenTargets

ENSG00000124635

GeneCards

P06899

HPA

ENSG00000124635-HIST1H2BJ

Ensembl

ENST00000607124, ENSG00000124635, ENSP00000476136, ENST00000339812, ENSP00000342886

PRO

P06899

PDB

3AZJ, 6K1J, 5AV8, 6T90, 3AZF, 6J51, 6L4A, 5CPJ, 3W98, 5Z23, 3AV1, 6HTS, 5XF5, 3AZH, 6A5P, 6JR0, 5AV5, 5GXQ, 6J4Z, 4YM5, 6YOV, 3AZN, 5AV9, 5JRG, 6A5L, 6A5T, 5Z30, 6E0C, 5XF4, 6IQ4, 3A6N, 5B2J, 5Y0C, 6T93, 6R93, 6J4X, 3AZE, 6JXD, 3AZL, 4CAY, 5CPI, 5B0Z, 3W96, 6R90, 5B40, 5B0Y, 6R91, 3WA9, 6BUZ, 6L49, 5AVC, 3AV2, 3AZI, 3AN2, 3AZM, 5GTC, 6O1D, 6K1K, 6KVD, 5AV6, 6R8Y, 5VEY, 6J4Y, 4YM6, 5B32, 6JOU, 5GSE, 6R94, 3AZG, 2RVQ, 6A5R, 6JR1, 6INQ, 6IR9, 6KXV, 6K1I, 5B24, 6HKT, 6J50, 5CPK, 6IPU, 3W99, 5ZBX, 6R92, 6J4W, 6A5O, 6A5U, 4Z5T, 5Y0D, 3AFA, 5B33, 6E0P, 5AVB, 5FUG, 5B2I, 3WAA, 3W97, 6R8Z, 5AY8, 3AZK, 5B31, 3AYW, 5XF3, 3WTP, 5X7X

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