SUMOylation of chromatin organization proteins

Stable Identifier
R-HSA-4551638
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

SUMOylation of proteins involved in chromatin organization regulates gene expression in several ways: direct influence on catalytic activity of enzymes that modify chromatin, recruitment of proteins that form repressive (e.g. PRC1) or activating complexes on chromatin, recruitment of proteins to larger bodies (e.g PML bodies) in the nucleus (reviewed in Cubenas-Potts and Matunis 2013).

Literature References
PubMed ID Title Journal Year
23328396 SUMO: a multifaceted modifier of chromatin structure and function Dev. Cell 2013
Participants
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Orthologous Events