SUMO2,3-K449,K577-RPA1 [nucleoplasm]

Stable Identifier
R-HSA-4551644
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
DNA Replication factor A protein A1 (70kD), RPA70, Replication protein A 70 kDa DNA-binding subunit, RP-A, RF-A, Replication factor-A protein 1, Single-stranded DNA-binding protein
SUMO2,3-K449,K577-RPA1 [nucleoplasm] icon
Locations in the PathwayBrowser for interactor UniProt:P23025 XPA
Literature References
PubMed ID Title Journal Year
24782567 Proteome-wide identification of SUMO2 modification sites

Tammsalu, T, Matic, I, Jaffray, EG, Ibrahim, AF, Tatham, MH, Hay, RT

Sci Signal 2014
External Reference Information
External Reference
Gene Names
RPA1, REPA1, RPA70
Chain
initiator methionine:1, chain:1-616, chain:2-616
Reference Transcript
Other Identifiers
11716571_at
11716572_s_at
1382_at
16829580
201528_at
201529_s_at
236675_at
3706001
3706002
3706003
3706006
3706007
3706008
3706010
3706017
3706018
3706019
3706020
3706021
3706022
3706023
3706024
3706026
3706028
3706029
3706032
3706033
3706034
3706035
38481_at
59166_at
6117
8003679
A_14_P107237
A_33_P3218951
GE58026
GO:0000003
GO:0000082
GO:0000228
GO:0000278
GO:0000723
GO:0000724
GO:0000784
GO:0003674
GO:0003676
GO:0003677
GO:0003684
GO:0003697
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005662
GO:0005694
GO:0006259
GO:0006260
GO:0006261
GO:0006268
GO:0006281
GO:0006283
GO:0006284
GO:0006289
GO:0006293
GO:0006294
GO:0006295
GO:0006296
GO:0006297
GO:0006298
GO:0006310
GO:0006950
GO:0006974
GO:0007004
GO:0007049
GO:0007165
GO:0008150
GO:0009058
GO:0016605
GO:0019985
GO:0022607
GO:0032201
GO:0032991
GO:0033683
GO:0034502
GO:0034641
GO:0036297
GO:0042276
GO:0042592
GO:0042769
GO:0043047
GO:0043167
GO:0043226
GO:0043565
GO:0046872
GO:0051276
GO:0051321
GO:0065003
GO:0070987
GO:0090734
GO:0098505
GO:1900034
GO:1901796
Hs.135292.0.A1_3p_at
Hs.84318.0.S2_3p_at
ILMN_1795719
ILMN_3249261
M63488_at
PH_hs_0004794
TC17000016.hg
TC17002004.hg
g4506582_3p_a_at
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 449
Coordinate
449
Modification
polySUMO2,3 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 577
Coordinate
577
Modification
polySUMO2,3 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
RefSeq
Target Pathogen
OpenTargets
GeneCards
ZINC - Substances
ZINC target
PRO
ZINC - Predictions - Purchasable
Interactors (16)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P15927 RPA2  2 0.939 12
 UniProt:P35244 RPA3  1 0.906 8
 UniProt:Q14191 WRN  2 0.818 9
 UniProt:P03070 LT      0.672 4
 UniProt:P38398 BRCA1  5 0.669 3
 UniProt:P54132 BLM  2 0.669 4
 UniProt:Q96LW4 PRIPO      0.623 7
 UniProt:P03116 VE1      0.558 2
 UniProt:Q5JR59-3 MTUS2      0.556 3
 UniProt:Q5JR59 MTUS2      0.556 3
 UniProt:P17066 HSPA6  5 0.556 3
 UniProt:Q9H9A7 RMI1  1 0.527 2
 UniProt:P23025 XPA  1 0.527 2
 UniProt:Q9UGP5 POLL  1 0.508 2
 UniProt:P02545 LMNA  3 0.462 2
 UniProt:P51587 BRCA2  2 0.462 3
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