RANBP2 SUMOylates RANBP2 at lysine-2592, lysine-2650, and lysine-2723 with SUMO1 (Pichler et al. 2002, Pichler et al. 2004, Cooper et al. 2005). RANBP2 does not resemble HECT or RING type SUMO E3 ligases and instead uses hydrophobic interactions with UBE2I (UBC9) to catalyze SUMOylation.
Pichler, A, Gast, A, Seeler, JS, Dejean, A, Melchior, F
Cooper, HJ, Tatham, MH, Jaffray, E, Heath, JK, Lam, TT, Marshall, AG, Hay, RT
Pichler, A, Knipscheer, P, Saitoh, H, Sixma, TK, Melchior, F
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