RANBP2 SUMOylates RANBP2 with SUMO2

Stable Identifier
R-HSA-4551679
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nuclear envelope, nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
RANBP2 SUMOylates RANBP2 with SUMO2
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

RANBP2 SUMOylates RANBP2 at lysine-2652 and lysine-2725 with SUMO2 (Cooper et al. 2005, Hendriks et al. 2014).

Literature References
PubMed ID Title Journal Year
25218447 Uncovering global SUMOylation signaling networks in a site-specific manner

Hendriks, IA, D'Souza, RC, Yang, B, Verlaan-de Vries, M, Mann, M, Vertegaal, AC

Nat. Struct. Mol. Biol. 2014
16194093 Fourier transform ion cyclotron resonance mass spectrometry for the analysis of small ubiquitin-like modifier (SUMO) modification: identification of lysines in RanBP2 and SUMO targeted for modification during the E3 autoSUMOylation reaction

Cooper, HJ, Tatham, MH, Jaffray, E, Heath, JK, Lam, TT, Marshall, AG, Hay, RT

Anal. Chem. 2005
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope]
Physical Entity
Nuclear Pore Complex (NPC) [nuclear envelope]
Activity
SUMO transferase activity (0019789)
Orthologous Events
RANBP2 SUMOylates RANBP2 with SUMO2 (Canis familiaris)
RANBP2 SUMOylates RANBP2 with SUMO2 (Danio rerio)
RANBP2 SUMOylates RANBP2 with SUMO2 (Mus musculus)
RANBP2 SUMOylates RANBP2 with SUMO2 (Rattus norvegicus)
RANBP2 SUMOylates RANBP2 with SUMO2 (Sus scrofa)
RANBP2 SUMOylates RANBP2 with SUMO2 (Xenopus tropicalis)
Authored
May, B  (2013-09-13)
Reviewed
Niskanen, E  (2018-05-09)
Niskanen, E  (2018-08-08)
Created
May, B  (2013-09-14)
Cite Us!