PIAS4 SUMOylates PARP1 at lysine-203 and lysine-486 with SUMO2,3 in response to heat shock (Martin et al. 2009, Lamoliatte et al. 2013, Hendriks et al. 2014, Tammsalu et al. 2014). PARP1 reciprocally poly(ADP-ribose)ylates PIAS4 (Martin et al. 2009). SUMOylation of PARP1 is required for full activation of the HSP70.1 promoter (Martin et al. 2009).
Tammsalu, T, Matic, I, Jaffray, EG, Ibrahim, AF, Tatham, MH, Hay, RT
Martin, N, Schwamborn, K, Schreiber, V, Werner, A, Guillier, C, Zhang, XD, Bischof, O, Seeler, JS, Dejean, A
Hendriks, IA, D'Souza, RC, Yang, B, Verlaan-de Vries, M, Mann, M, Vertegaal, AC
Lamoliatte, F, Bonneil, E, Durette, C, Caron-Lizotte, O, Wildemann, D, Zerweck, J, Wenshuk, H, Thibault, P
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