Reactome: A Curated Pathway Database

4SUMO2,3-BLM

Stable Identifier
R-HSA-4568883
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Bloom syndrome protein ecNumber3.6.4.12/ecNumber, BLM_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
External Reference Information
External Reference
Gene Names
BLM, RECQ2, RECQL3
Chain
chain:1-1417
Reference Genes
Reference Transcript
Other Identifiers
 0006290066  11756409_a_at  1544_at  16804902  205733_at
 2KV2  2MH9  2RRD  3608314  3608318
 3608321  3608322  3608323  3608324  3608326
 3608327  3608329  3608331  3608332  3608333
 3608335  3608336  3608338  3608339  3608340
 3608341  3608342  3608345  3608346  3608347
 3608349  3608351  3608352  3608353  3608354
 3608356  3608359  3608360  3608364  3608365
 3WE2  3WE3  4CDG  4CGZ  4O3M
 5689  5LUP  5MK5  641  7986068
 A_14_P114565  A_23_P88630  AAA87850  AAH93622  AAI01568
 AAI15031  AAI15033  AAW62255  AY886902  BC093622
 BC101567  BC115030  BC115032  BLM  BLM-201
 CCDS10363  ENSG00000197299  ENSP00000347232  ENST00000355112  EntrezGene:641
 g4557364_3p_at  GE62452  GO:0000079  GO:0000166  GO:0000228
 GO:0000278  GO:0000400  GO:0000403  GO:0000405  GO:0000724
 GO:0000729  GO:0000731  GO:0000732  GO:0000733  GO:0000781
 GO:0000800  GO:0002039  GO:0003674  GO:0003676  GO:0003677
 GO:0003678  GO:0003697  GO:0003824  GO:0004003  GO:0004386
 GO:0005515  GO:0005524  GO:0005575  GO:0005622  GO:0005623
 GO:0005634  GO:0005654  GO:0005657  GO:0005694  GO:0005730
 GO:0005737  GO:0005829  GO:0006259  GO:0006260  GO:0006281
 GO:0006310  GO:0006461  GO:0006464  GO:0006950  GO:0006974
 GO:0007049  GO:0007095  GO:0007165  GO:0008026  GO:0008150
 GO:0009058  GO:0009378  GO:0010165  GO:0016363  GO:0016605
 GO:0016787  GO:0016818  GO:0016887  GO:0022607  GO:0031297
 GO:0032508  GO:0034641  GO:0036310  GO:0042592  GO:0043140
 GO:0043167  GO:0043226  GO:0044237  GO:0044806  GO:0045893
 GO:0045910  GO:0048478  GO:0051259  GO:0051276  GO:0051301
 GO:0051782  GO:0051880  GO:0061749  GO:0061820  GO:0061821
 GO:0061849  GO:0065003  GO:0071479  GO:0072711  GO:0072757
 GO:0090656  GO:1901796  GO:1905773  HGNC:1058  HPA005689
 ILMN_1709484  IPR001650  IPR002121  IPR002464  IPR004589
 IPR010997  IPR011545  IPR011991  IPR012532  IPR014001
 IPR018982  IPR027417  IPR032284  IPR032437  IPR032439
 LRG_20  MIM:210900  MIM:604610  NM_000057  NM_001287246
 NM_001287248  NP_000048  NP_001274175  NP_001274177  PF00270
 PF00271  PF00570  PF08072  PF09382  PF16124
 PF16202  PF16204  PH_hs_0024362  SM00341  SM00487
 SM00490  SM00956  TC15000868.hg  U39817  U39817_at
 uc002bpr.5  UPI00001269FA  XM_006720632  XM_011521881  XP_006720695
 XP_011520183
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name Coordinate Modification PsiMod
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 317 317 polySUMO2,3 [nucleoplasm]
sumoylated lysine A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 347 347 polySUMO2,3 [nucleoplasm]
sumoylated lysine A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 331 331 polySUMO2,3 [nucleoplasm]
sumoylated lysine A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 344 344 polySUMO2,3 [nucleoplasm]
sumoylated lysine A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
UCSC human
ZINC - Substances
GeneCards
DOCK Blaster
ZINC target
PRO
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.805 Q9H9A7 RMI1_HUMAN 11
0.758 Q13472 TOP3A_HUMAN 6
0.691 Q15554 TERF2_HUMAN 8
0.672 Q9BX63 FANCJ_HUMAN 16
0.669 P27694 RFA1_HUMAN 4
0.655 Q14191 WRN_HUMAN 9
0.639 O75771 RA51D_HUMAN 4
0.611 P39748 FEN1_HUMAN 4
0.565 Q5UIP0 RIF1_HUMAN 6
0.558 P54274 TERF1_HUMAN 3
0.527 P35244 RFA3_HUMAN 2
0.527 P15927 RFA2_HUMAN 3
0.508 Q9NZN9 AIPL1_HUMAN 2
0.508 P51957 NEK4_HUMAN 2
0.462 Q96E14 RMI2_HUMAN 2